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c/coa·submitted 3 months ago by u/bastian_aalto

[Question] certificate of analysis — what am I missing here

Questionbranch of 9 comments

Slightly embarrassed to be asking this, but: certificate of analysis — what am I missing here. Spent four months confusing area% and mass% in every post I made here. One explainer thread and it clicked permanently. Water content 3.8%, acetate 6.2%, purity 99%, net peptide about 90% of label weight. All four numbers…

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9 comments, started 3 months ago
u/priya_palacios25 points·3 months ago

Did you ask for the batch-specific document, or is this the catalogue one?

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[deleted]9 points·3 months ago

[deleted]

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u/sunday_shot_sal4 points·3 months ago·edited

Agreed on asking for the storage condition. It is one line and it changes how you read the entire stability claim.

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u/cato_achebe3 points·3 months ago

That is not what the method line says. It names the technique; it does not certify the operator.

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u/kavya_verhoeven12 points·3 months ago

Agreed — the itemised related substances table is the difference between a document and a receipt.

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u/wanjiru_varga8 points·3 months ago

Small fix — 214nm, not 280nm. It matters here because the impurity you are asking about barely absorbs at the longer wavelength.

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u/vito_chowdhury8 points·3 months ago

chromatogram or it did not happen

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u/noor_cardoso15 points·3 months ago

My first certificate had a compound name, a percentage and a logo. I thought that was normal. It is not, and now I know what to ask for.

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u/nikhil_lindqvist5 points·3 months ago

post the whole document, not the headline number

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About c/coa

How to read a certificate of analysis and what it does and does not tell you. Area% versus mass%, identity versus quantity, water content, related substances, acetate counterions, and the difference between a vendor-supplied COA and an independent test on the vial you actually received.

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