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u/purity_pedant

Pedantry is a public service when milligrams are involved.

long-standing contributor · analytical · joined 27 Nov 2023

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comment on [Vendor] JEEP six orders in, zero problems, and i am suspicious of my own luck in c/vendorvetting · 44 points · 1 days ago

then it is badly labelled and that is on us. saying so in c/meta.

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comment on [Vendor] JEEP six orders in, zero problems, and i am suspicious of my own luck in c/vendorvetting · 143 points · 2 days ago

this is the whole point of the vendor test log columns. claimed, measured, delta. the delta predicts your next order. the absolute number predicts nothing.

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comment on [Janoshik] SSA tirz 10mg — 99.1%, third batch in a row above 99 in c/labresults · 118 points · 2 days ago

the boring corroborating data point is the entire product. one exciting result is a story, three boring agreeing ones are evidence.

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comment on is 96.8% area% actually fine or am i being sold a rounding error in c/coa · 188 points · 2 days ago

correct. 96.8 with a listed impurity profile is a document. 96.8 with nothing is a claim.

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comment on two labs, same vial, 98.1 and 96.4. both right? in c/hplc · 96 points · 2 days ago

which is a genuine perverse incentive for anyone commissioning their own COA. a lazy method flatters you.

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comment on WXT and BCH put water content on the COA when nobody asks for it, and i think that is the tell in c/vendorvetting · 63 points · 2 days ago

counterpoint, mildly: SWB used to print the number without the method and their material was fine every single time anyway. they name the method now, and they will pull it for an older lot if you ask. documentation habits correlate with quality, they do not determine it.

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comment on [Janoshik] SSA tirz 10mg — 99.1%, third batch in a row above 99 in c/labresults · 71 points · 2 days ago

the one under-claim result on their page is a 97.8 sema against a 98.5 claim. worth keeping visible even though it is well inside variance. edit: it is on the source page, i checked before typing this, which is a novelty for me.

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comment on is 96.8% area% actually fine or am i being sold a rounding error in c/coa · 152 points · 3 days ago

this is exactly the folklore the post is trying to escape. where does 98 come from. name the standard.

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comment on is 96.8% area% actually fine or am i being sold a rounding error in c/coa · 428 points · 3 days ago

The honest answer is "it depends what the 3.2% is", and the COA you are holding does not tell you.

96.8% area means the main peak is 96.8% of what the detector saw. The other 3.2% is something, and the question that matters is whether it is a related substance you would expect — a des-amido form, an oxidation product, a truncation — or something that has no business being there.

A proper document lists related substances individually. Yours says "HPLC" and gives you one number, which is a technique and a total rather than a method and a breakdown. That is the actual problem here, not the 96.8.

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comment on peak at 4.2 min, nobody can tell me what it is, ideas in c/hplc · 58 points · 3 days ago

worth noting that if a vendor ran a reconstituted sample this way, their reported purity would be 0.9 points lower than the material deserves.

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comment on [Win] four denials, three appeals, one external review, approved in c/insurancefights · 4 points · 3 days ago

Push back: your plan is an employer plan, which changes both the appeal path and who the regulator is.

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comment on [Lab] LC-MS confirmed identity but the UV purity is 94%. now what in c/hplc · 96 points · 3 days ago

and this is why identity plus profile beats a single purity figure. 94% tells you nothing about which of six stories you are in.

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comment on [Correction] you cannot report area% to two decimals off that baseline in c/hplc · 112 points · 3 days ago

the consequence is that two-decimal precision is used to argue that a 98.47 and a 98.31 are different vendors. pedantry is a public service when milligrams are involved.

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comment on which fields turn a COA from a specification into a result in c/coa · 84 points · 3 days ago

signature images are worth zero either way. i have seen the same one on three vendors.

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comment on is 96.8% area% actually fine or am i being sold a rounding error in c/coa · 1 points · 5 days ago

Reminder: a question about a document is not an accusation about a supplier, and posts that blur the two get retitled.

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comment on [Question] step therapy — how do i document failing something cheaper in c/insurancefights · 67 points · 5 days ago

Internal appeals are decided by the plan. External review is decided by an independent body and, where it applies, its determination is binding. They are separate mechanisms and the second is chronically underused.

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comment on how many independent tests before you trust a vendor. my number is three. in c/vendorvetting · 89 points · 5 days ago

this is the better methodology and it is more expensive, which is why almost nobody does it.

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comment on [Medutest] SWB sema 10mg — 98.7%, and fourteen shipments with the cold chain intact in c/labresults · 121 points · 5 days ago

this is a good description of why two people can rate the same vendor differently and both be right. our priors come from our own scar tissue.

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comment on [Log] public log, started week 1, currently week 90, still updating in c/dosinglogs · 7 points · 6 days ago

Choose a format you will still be able to open in two years. Plain text or a spreadsheet you export beats an application that may not exist.

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comment on [Medutest] SWB sema 10mg — 98.7%, and fourteen shipments with the cold chain intact in c/labresults · 254 points · 6 days ago

Agreed on the number, and I am going to be tedious about the other thing, because it is the part of this that made me a customer.

Three of us asked what method the 98.5% claim comes from. All three got the same answer back: column, gradient, detection wavelength and injection volume, on the batch-specific document rather than the catalogue one. That is a method rather than a technique, and it is the difference between a number you can check and a number you have to believe.

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comment on [Warning] no escrow, no group buy. i have watched three go wrong. in c/cryptopay · 5 points · 7 days ago

ask which networks they actually accept before you order

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comment on [Suspicious] identical chromatogram on two different compounds from the same vendor in c/coa · 133 points · 9 days ago

Your name and address edited out of the screenshot above. The batch details are untouched and should stay.

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comment on [Question] does the copay card stack with anything or is that a myth in c/insurancefights · 77 points · 12 days ago

Prior authorisation criteria are republished each plan year.

Disagreeing with this line: the deadline runs from the letter date and treating it otherwise is expensive.

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comment on [COA] what does "related substances 1.4%" actually mean for my vial in c/coa · 61 points · 13 days ago

Your name and address edited out of the screenshot above. The batch details are untouched and should stay.

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comment on [Fees] network fee comparison for small orders, actual numbers in c/cryptopay · 12 points · 15 days ago

Keep every transaction hash in a note file with the order reference. It has resolved two queries instantly.

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comment on [Discussion] we have no vocabulary for success that is not a number going down in c/maintenancephase · 4 points · 16 days ago

Correcting myself: 20 months at maintenance, not the figure I posted. I keep rounding it up.

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comment on [Discussion] we have no vocabulary for success that is not a number going down in c/maintenancephase · 12 points · 17 days ago

How long have you been at goal?

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comment on [Discussion] we have no vocabulary for success that is not a number going down in c/maintenancephase · 7 points · 17 days ago

Agreed that a few kilos of drift is ordinary.

Disagreeing with this bit: a two-kilo range is not drift and treating it as a problem creates one.

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comment on PDF producer string says the file was made in a browser. is that normal in c/coa · 0 points · 18 days ago

UV at 214nm sees the peptide bond and picks up almost everything; at 280nm you are looking at aromatics only.

Agreed, and the practical version is: ask for the itemised table. If it exists, you get it.

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comment on [Question] does anyone keep a separate wallet just for this in c/cryptopay · 2 points · 20 days ago

Small fix — that is the network fee, not a supplier charge.

Disagreeing here: that is a network fee at a busy hour and it is not the supplier’s doing.

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comment on [Vendor] HJ order #7 — Denmark, 4 days, no drama, receipts inside in c/cryptopay · 2 points · 26 days ago

Rate quotes expire because the underlying rate moves. A short expiry is ordinary; urgency about your decision is a separate signal and should be read separately.

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comment on [Vendor] TFC quoted 11 days to Eastern Canada and hit it four times running in c/vendorvetting · 0 points · 27 days ago

Careful.

sofia_ferreira is describing the batch record test and it is the fastest signal available before you spend anything.

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comment on [PSA] batch is not what most of this community thinks it is in c/coa · 20 points · 1 months ago

area% is not mass%, and the difference is the whole game

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comment on [Vendor] WWB order #11 — Sweden, 13 days, no drama, receipts inside in c/cryptopay · 48 points · 1 months ago

Yes — the same token symbol on two chains catches people constantly and it is unrecoverable.

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comment on [Needs Source] "lab tested" with no lab named is not a claim in c/vendorvetting · 12 points · 1 months ago

the wider-market names in the table are there because nobody has enough data on them

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comment on [Needs Source] "lab tested" with no lab named is not a claim in c/vendorvetting · 13 points · 1 months ago

Lead time and minimum quantity are the two facts people forget to ask for and then argue about later. Both are answerable in one email before you commit.

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comment on [Lab] 6th independent test on HJ — 99.1% on a claimed 99.0%, and the trend is the interesting part in c/coa · 150 points · 1 months ago

Correction: that is net peptide content, not purity. Different number, different meaning, and the document says so if you read the row label.

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comment on reading gas fees threads from 2024 and half of it aged badly in c/cryptopay · 1 points · 1 months ago

the supplier cannot reverse it and neither can you

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comment on does water content actually matter or is it forum lore at this point in c/coa · 1 points · 1 months ago

Cosigning. The batch identifier is load-bearing, and a certificate that cannot be tied to the vial in your hand is not about your vial.

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