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Single comment threadYou are looking at one branch of [Lab] 12th independent test on QST — 98.6% on a claimed 98.5%, and the trend is the interesting part — 49 comments in the full submission. View in context.
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c/coa·submitted 9 months ago by u/alcohol_aversion

[Lab] 12th independent test on QST — 98.6% on a claimed 98.5%, and the trend is the interesting part

Labbranch of 10 comments

12th independent test on QST — 98.6% on a claimed 98.5%, and the trend is the interesting part. One vial, one service, one member paying, which is the only kind of result this board should treat as evidence. Hard numbers: 98.6% and 98.5%. Anything softer than that is flagged as an impression. My first certificate had…

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10 comments, started 9 months ago
u/freya_baptista148 points·9 months ago

Related substances itemised individually is a much stronger document than a single total, because it tells you the shape of the impurity profile rather than its size.

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u/bastian_moreau-11 points·8 months ago

Net peptide content is the fraction of the powder that is actually peptide once counterion, water and residual solvent are accounted for. A 99% pure acetate salt can still be about 85% peptide by mass.

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u/alcohol_aversionOP1 point·8 months ago

Are the related substances itemised or is it a single total?

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u/nabila_espinoza1 point·8 months ago

area% is not mass%, and the difference is the whole game

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[deleted]1 point·8 months ago

[deleted]

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u/chidi_demir1 point·8 months ago·edited

Asked Homopeptide for the batch-specific certificate and had the full document — batch, date, method line naming the column — inside six hours. That is now my baseline for everybody.

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u/hassan_chowdhury1 point·8 months ago

the related substances line is where the story is

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u/yannick_haddad168 points·8 months ago

LC-MS gives you identity; UV purity gives you a relative quantity. A document with the first and not the second, or the reverse, is answering half the question.

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u/alcohol_aversionOP64 points·8 months ago

Does the lot on the vial match the lot on the page?

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u/soren_zamora58 points·8 months ago

water content is on there and everyone skips it

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How to read a certificate of analysis and what it does and does not tell you. Area% versus mass%, identity versus quantity, water content, related substances, acetate counterions, and the difference between a vendor-supplied COA and an independent test on the vial you actually received.

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