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c/bloodwork·submitted 1 year ago by u/kenji_kimani

what would you tell week-1 you about ALT

Concerningbranch of 6 comments

Genuine question, and the title is the question: what would you tell week-1 you about ALT. Panicked about a single result, posted here, got told to repeat it, repeated it, and it was fine. Tracked triglycerides against the weight trend for a year. The correlation was much weaker than I expected and that was worth…

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6 comments, started 1 year ago
u/mikkel_kimani90 points·1 year ago

Time of day, fasting state, hydration and recent exercise all move common markers. Standardising the draw conditions is free and it removes most of the apparent variability.

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u/iman_falk22 points·1 year ago·edited

Is that the same assay, or did the lab change platforms?

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u/coring_the_stopper62 points·1 year ago

Small fix — a reference interval is not a treatment target, and the post above uses them interchangeably.

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u/nabila_bakken41 points·1 year ago

Correction: that marker is reported in different units by different labs, which explains the tenfold difference you are seeing.

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u/anders_vermeulen20 points·1 year ago

same lab, same conditions, or you are comparing noise

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u/nnt_nate16 points·1 year ago

That comparison crosses two labs with different assays. The difference you are describing may be the method.

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What to measure before you start, what to re-measure, and how to interpret movement without panicking. ApoB over LDL-C, HOMA-IR as a crude free tool, ALT and the fatty-liver story, eGFR noise during rapid loss, and the deficiencies that a 1,100-calorie appetite will hand you.

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