[Explainer] HOMA-IR is crude and free, track it anyway
HOMA-IR is crude and free, track it anyway. If you already knew this, the post is not for you and you can scroll on.
ApoB counts atherogenic particles rather than the cholesterol they carry, which is why it can diverge from LDL-C and why it is the addition most worth making.
Time of day, fasting state, hydration and recent exercise all move common markers. Standardising the draw conditions is free and it removes most of the apparent variability.
Different laboratories use different assay platforms with different calibration. Comparing across labs adds a systematic offset that is invisible on the report.
Tell me where this is wrong. That is the useful part of posting it.
best — the order this archive was captured in
Substantial weight loss independently moves lipids, liver enzymes and several other markers. Attributing a change to a compound while losing weight is confounded by design.
Not convinced by the attribution. Weight loss alone moves that marker and you have no way to separate the two.
Draw at the same point in the week now, fasting, same lab. The noise dropped enormously once I standardised.
draw at the same point in the week if you want comparability
hydration status moves a surprising number of markers
Small fix — a reference interval is not a treatment target, and the post above uses them interchangeably.
Correction: that marker is reported in different units by different labs, which explains the tenfold difference you are seeing.
Correction: that marker is reported in different units by different labs, which explains the tenfold difference you are seeing.
Adding the obvious one — take it to whoever ordered the panel. This board cannot read it for you.
I would not draw a line through two points, especially when the second was taken at a different time of day.
- 1Not convinced by the attribution. Weight loss alone moves that marker and…8 comments in this branch · started by u/gustav_cardoso