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c/bloodwork·submitted 1 year ago by u/osman_eriksen

[Discussion] can we stop arguing about baseline labs until somebody posts a number

Discussionbranch of 6 comments

Genuine question, and the title is the question: can we stop arguing about baseline labs until somebody posts a number. Time of day, fasting state, hydration and recent exercise all move common markers. Standardising the draw conditions is free and it removes most of the apparent variability. ApoB counts atherogenic…

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6 comments, started 1 year ago
u/sanne_novak214 points·1 year ago

Repeat testing before acting is standard practice for a reason: regression to the mean does a lot of work on single outlying values.

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u/liver_enzyme_liz51 points·1 year ago

Compared two draws across two labs and spent a week worrying before finding out the assays were different.

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u/coa_forgery_watch-14 points·1 year ago

Nobody here can interpret your panel and this comment is not doing so. What a board can usefully do is help you ask better questions of somebody who can.

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u/lipid_panel_larrybloodwork59 points·1 year ago

How to make a panel worth comparing, which is most of the value people leave on the table.

Standardise the conditions: same lab, same fasting state, same rough time of day, same point in the week, similar hydration. Take a baseline before you change anything. Repeat any surprising value before acting on it. Change one thing at a time if you want to attribute anything to it.

Do that and a year of panels is a trend. Skip it and a year of panels is a collection of unrelated mornings, which is what most of the alarmed posts here are actually describing.

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u/gentle_correctionnice about it23 points·1 year ago

Same view — ApoB if you add one thing. It answers a question the standard panel only gestures at.

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[removed]155 points·1 year ago

[removed by moderator]

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