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c/bloodwork·submitted 2 years ago by u/karl_fischer_kev

[Discussion] can we stop arguing about ApoB until somebody posts a number

Discussionbranch of 11 comments

Question in the title, detail here: can we stop arguing about ApoB until somebody posts a number. Reference intervals are typically the central 95% of a reference population. By construction one person in twenty falls outside one on any given test without anything being wrong. Different laboratories use different…

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11 comments, started 2 years ago
u/gentle_correctionnice about it183 points·2 years ago

one measurement is a point, two is a line, three is a trend

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u/no_refunds_nr218 points·2 years ago

bring the numbers to someone qualified to read them

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u/blank_injection139 points·2 years ago

bring the numbers to someone qualified to read them

This is the sentence to read before anybody panics about a single value.

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u/lina_falk46 points·2 years ago

ApoB is the one worth adding if you only add one

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u/cold_chromatogram31101 points·2 years ago

do not change three things and then read the panel

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u/yara_boateng153 points·2 years ago

same lab, same conditions, or you are comparing noise

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u/cardio_endpoint_c122 points·2 years ago

ask whether the lab changed its assay between your two draws

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u/whois_wanda80 points·2 years ago

Not convinced by the attribution. Weight loss alone moves that marker and you have no way to separate the two.

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u/coa_forgery_watch20 points·2 years ago

draw at the same point in the week if you want comparability

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u/intent_to_treat59 points·2 years ago

ask whether the lab changed its assay between your two draws

Disagreeing with this bit: that change is confounded by the weight loss itself and cannot be attributed.

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u/chidi_abubakar28 points·2 years ago

Same view — ApoB if you add one thing. It answers a question the standard panel only gestures at.

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About c/bloodwork

What to measure before you start, what to re-measure, and how to interpret movement without panicking. ApoB over LDL-C, HOMA-IR as a crude free tool, ALT and the fatty-liver story, eGFR noise during rapid loss, and the deficiencies that a 1,100-calorie appetite will hand you.

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