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u/sofia_danquah

Contributes reviews on supplier material. Based in Rosario.

member · joined 14 May 2025

1,502post karma
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78comments

comment on [Pricing] compounded tirz pricing in my state, six months of receipts in c/compounding · 2 points · 3 days ago

ask which facility, then ask for their testing

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comment on TB-500 and Thymosin Beta-4 are not the same product and vendors know that in c/researchpeptides · 5 points · 4 days ago

Careful — that is a claim about efficacy and there is essentially no human evidence behind it.

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comment on [Trial Data] phase 2 biopsy endpoints, and what "resolution" means in c/survodutide · 14 points · 5 days ago

not approved anywhere, and the boards forget that constantly

dario_boateng is right that biopsy and imaging endpoints are not interchangeable.

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comment on telehealth prescriber asked me three questions and approved me. that is not care. in c/compounding · 17 points · 7 days ago

Careful. Naming a clinic without describing what actually happened turns this into a different kind of thread.

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comment on [COA] what does "related substances 1.4%" actually mean for my vial in c/coa · 1 points · 11 days ago

axis labels included, always

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comment on [Explainer] the four things a COA must have or it is decorative in c/coa · 95 points · 16 days ago

Net peptide content is the fraction of the powder that is actually peptide once counterion, water and residual solvent are accounted for. A 99% pure acetate salt can still be about 85% peptide by mass.

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comment on [Discussion] the GH secretagogue story is 30 years old and mostly a cautionary tale in c/researchpeptides · 8 points · 17 days ago

Stocked lines and made-to-order lines have different lead times and different storage histories.

This is the rule for anything unusual. Identity before anything else.

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comment on help me understand insulin syringe, I have read the wiki twice in c/reconstitution · 6 points · 18 days ago

20mg into 2mL is 10mg/mL, and 0.5mg of that is 5 units

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comment on help me understand insulin syringe, I have read the wiki twice in c/reconstitution · 2 points · 19 days ago

dead space in the needle hub is real and it is small

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comment on is it normal to get constipation at week 7 in c/survodutide · 36 points · 1 months ago

Imaging-derived liver fat fraction is a surrogate. It correlates with histology imperfectly, and a trial reporting one is not reporting the other.

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comment on someone explain concentration to me like I have not read a paper in years in c/reconstitution · -19 points · 1 months ago

Are you accounting for the powder volume, or is that where the confusion is?

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comment on help me understand purity, I have read the wiki twice in c/coa · 9 points · 1 months ago

Batch number and date of analysis, are both on there?

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comment on [Discussion] we are measuring state board at the wrong time and calling it noise in c/compounding · 6 points · 1 months ago

503A is patient-specific, 503B is outsourcing facility, they are not the same thing

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comment on genuine question about area percent that I am slightly embarrassed to ask in c/coa · 8 points · 2 months ago

That is the catalogue certificate rather than the batch-specific one. Same layout, completely different status.

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comment on API source — 17 things I got wrong before I got it right in c/compounding · 47 points · 2 months ago

That is not what patient-specific means. It refers to the prescription, not to a customisation of the formula.

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comment on [Question] France — has anyone got a straight answer on shipping in c/intlshipping · 24 points · 2 months ago

declared value and description are the shipper’s decision, ask what they use

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comment on help me understand water content, I have read the wiki twice in c/coa · 38 points · 2 months ago

Disagree that a lower number is automatically worse. A conservative claim that survives testing is worth more than an optimistic one that does not.

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comment on [Question] API source — what am I missing here in c/compounding · 21 points · 2 months ago

That is not what patient-specific means. It refers to the prescription, not to a customisation of the formula.

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comment on [Question] API source — what am I missing here in c/compounding · 18 points · 2 months ago

Asked for potency testing on the finished preparation.

Disagreeing with this bit: registration is not equivalence, and the two get run together constantly.

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comment on [Lab] 18th independent test on HJ — 99.2% on a claimed 99.0%, and the trend is the interesting part in c/coa · 20 points · 3 months ago

post the whole document, not the headline number

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comment on three years of shortage list threads, summarised so you do not have to read them in c/compounding · 7 points · 3 months ago

Right, and the concentration genuinely can differ from the branded product, which breaks people’s arithmetic.

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comment on [Meta] proposal — a flair for thymosin posts in c/researchpeptides · 1 points · 3 months ago

a secretagogue and a fragment are not the same class of thing

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comment on reading certificate of analysis threads from 2024 and half of it aged badly in c/coa · 0 points · 3 months ago

Pushing back a little: a missing field is usually presentation, not concealment. Ask for the full document before drawing conclusions.

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comment on how much of what we believe about what went wrong actually comes from failure threads in c/darkspot · 6 points · 4 months ago

going up too fast is the most repeated regret on this board

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comment on [PSA] purity is not what most of this community thinks it is in c/coa · 5 points · 4 months ago

Yes. The structure of the document matters at least as much as the number printed on it.

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comment on [PSA] regret is not what most of this community thinks it is in c/darkspot · 184 points · 4 months ago

Escalating faster than the schedule allows is the most frequently described regret on the site, and the mechanism is straightforward: tolerance is the limiting factor and it does not care about impatience.

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comment on [Vendor] GGPeps vs GL Biochem on the same compound, same month — both cleared 99.0% in c/coa · 32 points · 5 months ago

Pushing back a little: a missing field is usually presentation, not concealment.

low_appetite_lisa has the distinction right — one is a fraction of the detector signal, the other is a fraction of the mass.

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comment on reading secretagogue threads from 2024 and half of it aged badly in c/researchpeptides · 137 points · 5 months ago

What reference standard was the assay run against?

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comment on [Lab] 10th independent test on ERP — 97.2% on a claimed 97.0%, and the trend is the interesting part in c/coa · 120 points · 6 months ago

a certificate with no method line is decorative

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comment on [Discussion] handling is doing more work than we give it credit for in c/researchpeptides · 3 points · 7 months ago

Not convinced. A purity figure without a stated method is not comparable to one that has a method attached.

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comment on [Discussion] can we stop arguing about 503B until somebody posts a number in c/compounding · 32 points · 7 months ago

That figure is the starting material purity, not the finished preparation potency. Two different tests.

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comment on [Question] Ireland — has anyone got a straight answer on 503B in c/compounding · 5 points · 7 months ago

Push back: "compounded is fine because a pharmacy made it" skips every question this board exists to ask.

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comment on [Question] how do you actually verify EMS in c/intlshipping · 15 points · 8 months ago

no tracking numbers, ever

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comment on the 503A question that gets asked weekly, answered properly in c/compounding · 55 points · 9 months ago

I would not read the price difference as a quality signal. Most of it is the consultation model, not the vial.

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comment on [Discussion] can we stop arguing about water content until somebody posts a number in c/coa · 45 points · 10 months ago

area% is not mass%, and the difference is the whole game

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comment on [Discussion] can we stop arguing about water content until somebody posts a number in c/coa · 61 points · 10 months ago

Area percent or net peptide content? They answer different questions.

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comment on [Discussion] can we stop arguing about water content until somebody posts a number in c/coa · 21 points · 10 months ago

Pushing back a little: a missing field is usually presentation, not concealment. Ask for the full document before drawing conclusions.

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comment on my ALT moved and I cannot work out whether dual agonist is why in c/survodutide · 34 points · 10 months ago

Not convinced. Imaging-based fat fraction is not the same as a histological response and the paper is explicit about that.

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comment on reading 503A threads from 2024 and half of it aged badly in c/compounding · 7 points · 11 months ago

Yes — asking which facility, by name, is the single most useful question and most clinics will answer it.

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comment on reading 503A threads from 2024 and half of it aged badly in c/compounding · 137 points · 11 months ago

Paid noticeably more at one clinic than another for what turned out to be the same facility behind both.

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