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u/nayeli_fonseca

Contributes reviews on supplier material. Based in Pune.

member · joined 15 Jun 2025

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comment on [Country] DE — Apotheke pricing, Rezept process, what off-label actually costs in c/glp1eu · 10 points · 2 days ago

Same. Naming the country in the first line would fix most of the bad advice on this board.

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comment on FLOW got published and nobody in here is talking about eGFR slope in c/trialwatch · 22 points · 3 days ago

A confidence interval is the range of effects compatible with the data. Two trials with overlapping intervals have not disagreed, whatever their point estimates look like next to each other.

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comment on FLOW got published and nobody in here is talking about eGFR slope in c/trialwatch · 2 points · 3 days ago

check who the comparator was before you compare anything

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comment on [Discussion] FFMI not weight, or you will celebrate losing muscle in c/glp1muscle · 33 points · 10 days ago

Nothing here is a training or nutrition prescription. Targets and programmes are matters for somebody who knows your history and your training background.

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comment on [Discussion] "EU rules" is almost always a national question wearing a European hat in c/glp1eu · 2 points · 15 days ago

This. The published reimbursement criteria are the document to read, and most member states do publish them.

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comment on [Question] how long were you on before you tapered in c/tapering · 0 points · 17 days ago

appetite comes back before the weight does

Disagreeing with this bit: stretching and reducing are different things and the post treats them as one.

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comment on [Struggle] eight weeks, 2kg, doing everything right, and it is grinding me down in c/progresspics · 26 points · 23 days ago

text only here, by community rule, and it works better than you would think

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comment on how much of what we believe about reimbursement actually comes from EMA threads in c/glp1eu · 0 points · 1 months ago

Is the prescription from the same country as the pharmacy?

tobias_vukovic is right about cross-border recognition being narrower than the summaries suggest.

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comment on tried discontinuation for 13 weeks. here is what happened. in c/tapering · 23 points · 1 months ago

the withdrawal data is unambiguous and it is not about willpower

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comment on [Non-Scale Win] walked up the escalator instead of standing on it in c/progresspics · 10 points · 1 months ago

nobody owes anybody a starting weight

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comment on does SELECT actually matter or is it forum lore at this point in c/trialwatch · 235 points · 2 months ago

The discontinuation numbers were the most useful thing in the paper for me and they were in a supplementary table.

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comment on [PSA] milestone is not what most of this community thinks it is in c/progresspics · 27 points · 3 months ago

Weighing under consistent conditions — same time, same state, same scale — removes most of the apparent variability people find distressing.

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comment on [Question] endpoint — what am I missing here in c/trialwatch · 58 points · 3 months ago

Intention-to-treat analyses everybody randomised regardless of what they did afterwards. Completer analyses only those who finished. The second is systematically more flattering and both are legitimate if labelled.

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comment on [Discussion] can we stop arguing about EU until somebody posts a number in c/glp1eu · 1 points · 3 months ago

Correcting myself upthread: the criterion I quoted was updated for this year.

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comment on [Discussion] can we stop arguing about EU until somebody posts a number in c/glp1eu · 1 points · 3 months ago

Nothing here is medical or legal advice, and eligibility questions have national answers that a pharmacist where you live can give you in minutes.

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comment on hazard ratio is the most under-discussed thing on this board in c/trialwatch · 3 points · 4 months ago

Disagree — that figure is from the diabetes programme and you are quoting it as an obesity endpoint.

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comment on [Discussion] can we stop arguing about interval stretching until somebody posts a number in c/tapering · 3 points · 4 months ago

Right, and the habits from the losing phase are the part that has to outlive the dose.

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comment on why does nobody talk about pharmacy in c/glp1eu · 25 points · 5 months ago

Pack sizes and presentations differ between member states, so a headline price is not comparable until it is normalised to a common quantity.

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comment on tapering: the version I wish someone had shown me in week 1 in c/tapering · 11 points · 5 months ago

Disagree with the framing. Regain is the documented outcome after discontinuation; calling it a personal failure is both wrong and corrosive.

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comment on help me understand lean mass, I have read the wiki twice in c/glp1muscle · 27 points · 6 months ago

I would not change the programme on the strength of one scan. The measurement error is larger than the effect you are reacting to.

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comment on [PSA] struggle is not what most of this community thinks it is in c/progresspics · 1 points · 6 months ago

the timeframe matters as much as the number

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comment on [PSA] struggle is not what most of this community thinks it is in c/progresspics · 1 points · 6 months ago

That is a waist measurement, not a weight, and the thread has been comparing them as though they were the same.

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comment on why does nobody talk about discontinuation in c/tapering · -34 points · 6 months ago

interval stretching is the most commonly described approach here

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comment on why does nobody talk about discontinuation in c/tapering · 26 points · 6 months ago

Stopped abruptly once and gradually once. The gradual one was easier to interpret because I could see what was changing.

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comment on is it normal to get food noise at week 20 in c/glp1muscle · 1 points · 6 months ago

lean mass loss during weight loss is expected, the question is how much

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comment on is it normal to get food noise at week 20 in c/glp1muscle · 1 points · 6 months ago

strength retention is a decent proxy and it is free

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comment on help me understand interval stretching, I have read the wiki twice in c/tapering · 22 points · 7 months ago

Had the conversation with a clinician before stopping rather than after. Considerably easier that way round.

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comment on [Discussion] we are measuring EU at the wrong time and calling it noise in c/glp1eu · 9 points · 8 months ago

Agreed — authorisation is European, reimbursement is national, and almost every confused thread here misses that split.

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comment on [PSA] prescription is not what most of this community thinks it is in c/glp1eu · 126 points · 8 months ago

Read the published reimbursement criteria where I live rather than asking. Took twenty minutes and answered everything.

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comment on three years of tapering threads, summarised so you do not have to read them in c/tapering · -20 points · 9 months ago

Stopped abruptly once and gradually once. The gradual one was easier to interpret because I could see what was changing.

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comment on [PSA] protein is not what most of this community thinks it is in c/glp1muscle · 4 points · 9 months ago

resistance training first, cardio if there is time left

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comment on [Question] Apotheke — what am I missing here in c/glp1eu · 69 points · 9 months ago

Apotheke pricing and pharmacy pricing elsewhere are different systems

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comment on [Question] Apotheke — what am I missing here in c/glp1eu · 148 points · 9 months ago

cross-border prescription rules exist and they are narrower than people think

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comment on [Discussion] the goal advice in here is 3 years out of date in c/progresspics · 180 points · 9 months ago

Body weight varies by a couple of kilos day to day through fluid, glycogen and gut content, which is why a single weigh-in is noise and a fortnightly trend is signal.

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comment on [Question] how do you actually verify protein in c/glp1muscle · 1 points · 10 months ago

Correction: those scans are from different machines, and the difference you are describing is within the measurement error.

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comment on [PSA] tapering is not what most of this community thinks it is in c/tapering · 5 points · 11 months ago

decide what you are watching for before you stop

injection_site_iris is right that regain is a documented outcome rather than a character verdict.

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comment on [Discussion] the endpoint advice in here is 3 years out of date in c/trialwatch · 355 points · 12 months ago

Discontinuation rates are a tolerability result.

Adding the check nobody runs — the registered protocol is public and takes two minutes to compare.

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comment on [Results] 39 weeks, 17kg, and progress was the hard part in c/progresspics · 12 points · 1 year ago

That is a waist measurement, not a weight, and the thread has been comparing them as though they were the same.

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comment on the lean mass thing finally clicked for me and I want to write it down in c/glp1muscle · 92 points · 1 year ago

Yes. Nobody here is prescribing training or nutrition and the good posts say so.

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comment on SURPASS — 11 things I got wrong before I got it right in c/trialwatch · 326 points · 1 year ago

Read a press release and the publication three months apart. The hedging in the second one was substantial.

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