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u/nadia_kjaer

Contributes reviews on supplier material. Based in Cork.

member · joined 12 Mar 2025

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Overview — page 3 of 3

comment on [Discussion] can we stop arguing about reconstitution until somebody posts a number in c/reconstitution · 156 points · 1 year ago

Shook the first vial because nobody told me not to. It was fine, but I have swirled every one since.

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comment on [Discussion] can we stop arguing about bacteriostatic water until somebody posts a number in c/reconstitution · 431 points · 1 year ago

Did the maths give you a whole number of units, or a fraction?

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comment on [Discussion] can we stop arguing about bacteriostatic water until somebody posts a number in c/reconstitution · 1 points · 1 year ago

I would not round that figure.

Adding one thing — put the date on the label too. Concentration plus date and you can never mix two vials up.

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comment on [Discussion] the chargeback advice in here is 3 years out of date in c/cryptopay · 15 points · 1 year ago

Some chains require a memo or destination tag to route funds to the right account.

Agreed — and the hash is the receipt. Nothing else is.

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comment on three years of water content threads, summarised so you do not have to read them in c/coa · 209 points · 1 year ago

Net peptide content is the fraction of the powder that is actually peptide once counterion, water and residual solvent are accounted for.

rohan_steiner has the distinction right — one is a fraction of the detector signal, the other is a fraction of the mass.

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comment on [Question] mg/mL — what am I missing here in c/reconstitution · 97 points · 1 year ago

That only works if the fill weight is exactly the label weight, and it usually is not exactly anything.

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comment on glucagon is the most under-discussed thing on this board in c/survodutide · 174 points · 1 year ago

It is a dual agonist at the GLP-1 and glucagon receptors. The glucagon arm is associated with increased energy expenditure and with effects on hepatic fat, which is why the development programme is oriented towards liver disease.

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comment on how much of what we believe about chargeback actually comes from crypto threads in c/cryptopay · 24 points · 1 year ago

network and address, checked twice, before anything else

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comment on [Discussion] the excursion advice in here is 2 years out of date in c/coldchain · 126 points · 1 year ago

Right, and asking what the stability statement was written against is one line of email that reframes everything.

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comment on someone explain dead space to me like I have not read a paper in years in c/reconstitution · 103 points · 2 years ago

Disagree with the "more water is safer" framing. It is not safer, it is just a different number to divide by.

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comment on the gas fees question that gets asked weekly, answered properly in c/cryptopay · 12 points · 2 years ago

Correction: that address format is not the chain you named. Worth checking before anybody follows this.

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comment on [Discussion] mg/mL is doing more work than we give it credit for in c/reconstitution · 2 points · 2 years ago

Show the arithmetic — where did the unit figure come from?

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comment on why does nobody talk about biopsy in c/survodutide · 96 points · 2 years ago

Histological endpoints in this field are scored on biopsy: resolution of steatohepatitis without worsening of fibrosis, or improvement in fibrosis without worsening of steatohepatitis. Both are harder to achieve and to interpret than an imaging surrogate.

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comment on how much of what we believe about COA actually comes from area percent threads in c/coa · 20 points · 2 years ago

Cosigning. The batch identifier is load-bearing, and a certificate that cannot be tied to the vial in your hand is not about your vial.

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comment on [Discussion] the mg/mL advice in here is 3 years out of date in c/reconstitution · 47 points · 2 years ago

dead space in the needle hub is real and it is small

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comment on [Lab] 16th independent test on WXT — 99.3% on a claimed 98.5%, and the trend is the interesting part in c/coa · 147 points · 2 years ago

LC-MS gives you identity; UV purity gives you a relative quantity. A document with the first and not the second, or the reverse, is answering half the question.

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comment on bacteriostatic water — 16 things I got wrong before I got it right in c/reconstitution · 28 points · 2 years ago

5mg into 3mL is 1.67mg/mL, and 0.5mg of that is 30 units

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comment on [Discussion] the area percent advice in here is 2 years out of date in c/coa · 18 points · 2 years ago

Right, and net peptide content is where the counterion and the water go. Both numbers can be honest and very different.

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