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u/draw_up_dizzy

Air bubble anxiety in an insulin syringe is not proportional to the risk.

newer member · joined 31 Mar 2025

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comment on [Formulary] provincial differences, mapped, with dates in c/glp1canada · 1 points · 1 days ago

Have you seen the special authorization criteria for your province?

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comment on [Paper] survodutide MASH data is the most interesting hepatic readout in the class in c/survodutide · 15 points · 2 days ago

glucagon agonism and energy expenditure is the mechanistic thread

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comment on [Pricing] compounded tirz pricing in my state, six months of receipts in c/compounding · 7 points · 2 days ago

Asked for the beyond-use date basis and got a real answer with a stability reference attached. Not universal, apparently.

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comment on [Pricing] compounded tirz pricing in my state, six months of receipts in c/compounding · 44 points · 4 days ago

ask what the beyond-use date is based on

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comment on [Trial Data] phase 2 biopsy endpoints, and what "resolution" means in c/survodutide · 41 points · 5 days ago

glucagon agonism and energy expenditure is the mechanistic thread

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comment on [Question] protein target in g/kg — of current weight or goal weight in c/glp1muscle · 8 points · 7 days ago

Cosigning that protein gets harder precisely when appetite drops. That is the actual difficulty and it is logistical.

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comment on intent-to-treat vs per-protocol explains half the arguments on this site in c/trialwatch · 16 points · 12 days ago

This. Intention-to-treat versus completer analysis routinely moves the headline by several points.

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comment on [Stats] number needed to treat, or i am not interested in c/trialwatch · 74 points · 19 days ago

Argued for a week about a result and then read the limitations section, which conceded most of my opponent’s point.

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comment on [Results] two years, weight stable within 3kg, dose at a quarter of peak in c/maintenancephase · 6 points · 22 days ago

plan the maintenance phase before you need it

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comment on [Question] shortage list — what am I missing here in c/compounding · 52 points · 23 days ago

potency testing on the finished preparation is the thing to ask for

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comment on [Long Term] what my labs look like three years in in c/maintenancephase · 1 points · 27 days ago

monthly weigh-ins are enough at this stage

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comment on three years of SURMOUNT threads, summarised so you do not have to read them in c/trialwatch · 2 points · 27 days ago

discontinuation rate is a result, not a footnote

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comment on [Long Term] what my labs look like three years in in c/maintenancephase · 20 points · 27 days ago

Same. Monthly is plenty at this stage and daily weighing made me miserable for no information gain.

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comment on three years of SURMOUNT threads, summarised so you do not have to read them in c/trialwatch · 10 points · 29 days ago

read the endpoint before you read the headline

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comment on [Announcement] wiki rewrite finished — 22 community wikis live in c/meta · 1 points · 29 days ago

vendor source pages link storefronts and the link is marked

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comment on [Question] France — has anyone got a straight answer on telehealth in c/compounding · 1 points · 1 months ago

503A is patient-specific, 503B is outsourcing facility, they are not the same thing

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comment on [Lab] GGPeps survo — VendorInvestigate came back 97.9% against a claimed 97.0% in c/survodutide · 4 points · 1 months ago

Same. Very thin independent data on this one, which should make everybody here more tentative than they are.

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comment on [Lab] GGPeps survo — VendorInvestigate came back 97.9% against a claimed 97.0% in c/survodutide · 49 points · 1 months ago

Assumed the weight numbers were the point and was corrected. They are secondary to what this is being developed for.

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comment on [Rules] no referral links. not once. not ever. permanent. in c/meta · 3 points · 1 months ago

evidence rules are strict here on purpose

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comment on [Rules] no referral links. not once. not ever. permanent. in c/meta · 52 points · 1 months ago

Edited a wiki page for the first time and nothing bad happened, which is apparently the point.

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comment on [Results] 48 weeks, 18kg, and DEXA was the hard part in c/glp1muscle · 3 points · 2 months ago

Are you comparing against your own baseline or against a published average?

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comment on reading protein threads from 2024 and half of it aged badly in c/glp1muscle · 2 points · 2 months ago

Yes.

Agreed — and same machine, same conditions, or the two scans are not comparable.

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comment on how much of what we believe about endpoint actually comes from FLOW threads in c/trialwatch · 34 points · 2 months ago

intention to treat versus completers changes the number substantially

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comment on state board — 3 things I got wrong before I got it right in c/compounding · 26 points · 2 months ago

Concentration on the compounded vial was different from what I had been using and I nearly did the arithmetic on autopilot.

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comment on state board — 3 things I got wrong before I got it right in c/compounding · 1 points · 2 months ago

This. Compounded preparations carry no equivalence claim, and treating them as generics is a category error people make constantly.

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comment on three years of private plan threads, summarised so you do not have to read them in c/glp1canada · 5 points · 3 months ago

Formulary criteria are revised, and plan renewal is a natural point at which a previously refused request may succeed without anything about the appli

Disagreeing with this line: that is an employer plan process and the provincial one differs.

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comment on [Question] Canada — what am I missing here in c/glp1canada · 4 points · 3 months ago

Moved provinces and the coverage position changed completely. Same person, same history, different formulary.

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comment on [Question] Canada — what am I missing here in c/glp1canada · 12 points · 3 months ago

Was this a denied authorization or a rejected claim?

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comment on [Question] Canada — what am I missing here in c/glp1canada · 14 points · 3 months ago

Have you asked the pharmacist to check?

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comment on unpopular opinion: most of what gets said here about telehealth is guesswork in c/compounding · 7 points · 3 months ago

Did they name the facility?

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comment on [PSA] private plan is not what most of this community thinks it is in c/glp1canada · 12 points · 3 months ago

the criteria change at plan renewal and nobody announces it

Agreed — write the application against the published criteria rather than around them.

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comment on [Discussion] the wiki advice in here is 3 years out of date in c/meta · 6 points · 4 months ago

Checked the sponsor disclosure because I assumed it would be vague. It was extremely specific and slightly boring.

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comment on [Discussion] the wiki advice in here is 3 years out of date in c/meta · 1 points · 4 months ago

Read the ranking formula out of scepticism and reproduced the ordering in a spreadsheet. It does what it says.

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comment on help me understand sarcopenia, I have read the wiki twice in c/glp1muscle · 1 points · 4 months ago

Have the lifts held, dropped, or moved around?

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comment on [Question] Canada — has anyone got a straight answer on special authorization in c/glp1canada · 8 points · 4 months ago

Yes. Approval and coverage are separate, and this board conflates them in about half its threads.

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comment on Canada: API source, and what it actually costs here in c/compounding · 2 points · 4 months ago

the shortage list is the whole legal hinge and people skip it

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comment on how much of what we believe about endpoint actually comes from TRIUMPH threads in c/trialwatch · 152 points · 4 months ago

Agreed.

hub_ops is right about the programme names. They are different populations with different endpoints.

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comment on [Question] how do you actually verify MASH in c/survodutide · 99 points · 4 months ago

Spent an evening on the histology scoring system and understood the trial literature far better afterwards.

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comment on [Question] how do you actually verify moderation in c/meta · 1 points · 4 months ago

the archive-after-a-year policy is deliberate

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comment on genuine question about API source that I am slightly embarrassed to ask in c/compounding · 5 points · 4 months ago

Yes — asking which facility, by name, is the single most useful question and most clinics will answer it.

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