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u/anjali_tamm

Contributes reviews on supplier material. Based in Setúbal.

member · joined 12 Mar 2025

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48comments

comment on [Data] logger trace: 6 days transit, 41 hours above 8°C, powder was fine in c/coldchain · 41 points · 4 days ago

Yes — a logger in the box turns a fortnight of speculation into a chart.

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comment on sterile water is not bacteriostatic water and it is not close in c/reconstitution · 364 points · 6 days ago

Adding more water does not change how much peptide is in the vial. It changes the concentration, which changes the volume you draw for the same amount. That is the entire relationship.

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comment on £18 USB logger settled a three-week argument in thirty seconds in c/coldchain · 1 points · 7 days ago

Was there a logger in the box?

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comment on someone explain units to me like I have not read a paper in years in c/reconstitution · 6 points · 20 days ago

aim the stream at the glass wall, not at the cake

Adding one thing — put the date on the label too. Concentration plus date and you can never mix two vials up.

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comment on someone explain lyophilised to me like I have not read a paper in years in c/coldchain · 3 points · 1 months ago

insulation buys hours, not days

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comment on help me understand mg/mL, I have read the wiki twice in c/reconstitution · 426 points · 1 months ago

If your calculation produces a fraction of a unit, the concentration is wrong for your dose. Change the water volume until the numbers land on whole units.

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comment on the bacteriostatic water thing finally clicked for me and I want to write it down in c/reconstitution · 93 points · 1 months ago

more water is not more drug, it is the same drug in a bigger volume

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comment on three years of reconstitution threads, summarised so you do not have to read them in c/reconstitution · 45 points · 1 months ago

How many mg in the vial and how many mL are you adding?

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comment on [Discussion] the bacteriostatic water advice in here is 3 years out of date in c/reconstitution · 24 points · 1 months ago

I keep a laminated card in the drawer with the arithmetic on it. Looks ridiculous. Has never once let me draw the wrong volume.

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comment on [PSA] cold chain is not what most of this community thinks it is in c/coldchain · 130 points · 2 months ago

Ordered from the warehouse in Australia instead of origin and the transit went from a fortnight to 10 days. Entirely different proposition in August.

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comment on the excursion thing finally clicked for me and I want to write it down in c/coldchain · 52 points · 2 months ago

I would not freeze it in solution. That is a different failure mode and a worse one.

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comment on how much of what we believe about bacteriostatic water actually comes from dead space threads in c/reconstitution · 1 points · 4 months ago

dead space in the needle hub is real and it is small

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comment on [Discussion] units are doing more work than we give it credit for in c/reconstitution · 111 points · 5 months ago

Adding more water does not change how much peptide is in the vial. It changes the concentration, which changes the volume you draw for the same amount. That is the entire relationship.

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comment on Spain: cold chain, and what it actually costs here in c/coldchain · 3 points · 5 months ago

A transit temperature logger records a distribution, and time above a threshold matters as much as peak temperature. That is the argument for logging rather than guessing.

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comment on excursion — 20 things I got wrong before I got it right in c/coldchain · 1 points · 6 months ago

fridge, not freezer, once it is in solution

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comment on does data logger actually matter or is it forum lore at this point in c/coldchain · 26 points · 7 months ago

Wrote the reconstitution date on the vial for the first time last year. Have never once since wondered how old a solution is.

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comment on [Question] how do you actually verify units in c/reconstitution · 587 points · 10 months ago

I would not round that figure. At 30mg/mL a rounding error of two units is a real fraction of the intended amount.

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comment on unpopular opinion: most of what gets said here about dead space is guesswork in c/reconstitution · 8 points · 11 months ago

Wrote the date on the vial as well as the concentration after losing track of which one was opened first.

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comment on Spain: data logger, and what it actually costs here in c/coldchain · 6 points · 11 months ago

a summer lane and a winter lane are different lanes

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comment on [Discussion] the reconstitution advice in here is 3 years out of date in c/reconstitution · 59 points · 11 months ago

I keep a laminated card in the drawer with the arithmetic on it. Looks ridiculous. Has never once let me draw the wrong volume.

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comment on the insulin syringe thing finally clicked for me and I want to write it down in c/reconstitution · 1 points · 12 months ago

Wrote the date on the vial as well as the concentration after losing track of which one was opened first.

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comment on lyophilised — 8 things I got wrong before I got it right in c/coldchain · 5 points · 1 year ago

You cannot infer potency from a temperature record. The record tells you what happened to the box; only a test tells you what happened to the material.

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comment on [Question] how do you actually verify bacteriostatic water in c/reconstitution · 8 points · 1 year ago

Pushback on the syringe advice: a U-100 barrel reads units of volume. Calling them "doses" is how the confusion starts.

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comment on [PSA] units are not what most of this community thinks it is in c/reconstitution · 72 points · 1 year ago

Started reconstituting everything to a round concentration and the six-in-the-morning error rate went to zero.

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comment on [Question] data logger — what am I missing here in c/coldchain · 23 points · 1 year ago

How many days in transit, and which month?

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comment on Germany: data logger, and what it actually costs here in c/coldchain · 15 points · 1 year ago

the excursion that matters is the one after reconstitution

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comment on [Question] reconstitution — what am I missing here in c/reconstitution · 9 points · 1 year ago

Pushback on the syringe advice: a U-100 barrel reads units of volume. Calling them "doses" is how the confusion starts.

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comment on [Question] reconstitution — what am I missing here in c/reconstitution · 11 points · 1 year ago

Research-use-only material is not approved for human use, so treat everything in this thread as arithmetic about solutions rather than instructions for a person.

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comment on [Discussion] can we stop arguing about reconstitution until somebody posts a number in c/reconstitution · 73 points · 1 year ago

Working has to be shown on arithmetic posts.

units_not_mg has the units point exactly right. They are a volume on the barrel and nothing else.

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comment on [Discussion] the packaging advice in here is 2 years out of date in c/coldchain · 91 points · 1 year ago

a summer lane and a winter lane are different lanes

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comment on does concentration actually matter or is it forum lore at this point in c/reconstitution · 646 points · 1 year ago

Aim the stream down the wall of the vial rather than into the cake. Reconstitution is a solubility problem, not a mixing problem, and mechanical shear does nothing helpful.

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comment on [Question] mg/mL — what am I missing here in c/reconstitution · 87 points · 1 year ago

Adding more water does not change how much peptide is in the vial. It changes the concentration, which changes the volume you draw for the same amount. That is the entire relationship.

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comment on the stability question that gets asked weekly, answered properly in c/coldchain · 11 points · 2 years ago

a logger costs less than a vial and answers the question permanently

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comment on [Meta] proposal — a flair for units posts in c/reconstitution · 198 points · 2 years ago

a U-100 syringe reads 100 units to the millilitre, every time

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comment on [Meta] proposal — a flair for cold chain posts in c/coldchain · 4 points · 2 years ago

What was the packaging — rigid outer, gel packs, anything insulating?

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comment on [Meta] proposal — a flair for cold chain posts in c/coldchain · 37 points · 2 years ago

a warm gel pack tells you the pack failed, not that the material did

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comment on [Discussion] the mg/mL advice in here is 3 years out of date in c/reconstitution · 3 points · 2 years ago

if the maths gives you a fraction of a unit, change the concentration

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comment on [Discussion] we are measuring mg/mL at the wrong time and calling it noise in c/reconstitution · 339 points · 2 years ago

Right — the volume you add is the only variable you control here, and the cake does not change it meaningfully.

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comment on [Discussion] we are measuring mg/mL at the wrong time and calling it noise in c/reconstitution · 89 points · 2 years ago

Cosigning the round-number approach. Reconstituting to something awkward is how you end up drawing 27.5 units at six in the morning.

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comment on dead space — 16 things I got wrong before I got it right in c/reconstitution · 68 points · 2 years ago

a U-100 syringe reads 100 units to the millilitre, every time

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