does SELECT actually matter or is it forum lore at this point
Asking properly rather than in a comment on somebody else’s thread: does SELECT actually matter or is it forum lore at this point. Compared myself to a trial mean for about six months before realising the trial arm had dietitian contact every fortnight. On means, which this board treats as targets and which are…
Relative risk reduction without the baseline rate is uninterpretable. A large relative reduction on a small absolute risk is a small absolute benefit.
Absolute or relative risk reduction?
open-label extensions are not the same evidence as the randomised phase
check who the comparator was before you compare anything
open-label extensions are not the same evidence as the randomised phase
Agreed. And the interval, not the point estimate, is what the trial actually established.
read the endpoint before you read the headline
A confidence interval is the range of effects compatible with the data. Two trials with overlapping intervals have not disagreed, whatever their point estimates look like next to each other.
Read a press release and the publication three months apart. The hedging in the second one was substantial.