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c/trialwatch·submitted 3 months ago by u/nhs_waitlist_n

the STEP question that gets asked weekly, answered properly

Statsbranch of 7 comments

Something I keep coming back to: the STEP question that gets asked weekly, answered properly. Cardiovascular outcome trials are powered for events, not for weight, and are typically run in a different population with different inclusion criteria. Reading a weight number out of one is reading a secondary endpoint. The…

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7 comments, started 3 months ago
u/annika_fonseca8 points·3 months ago

SURPASS is the diabetes programme and reports glycaemic endpoints

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u/nhs_waitlist_nOPUK4 points·3 months ago

How long was the randomised phase before any extension?

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u/hugo_norgaard5 points·3 months ago

check who the comparator was before you compare anything

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u/injection_site_iris4 points·3 months ago

Spent an evening with the appendix tables and found the subgroup detail that the entire thread had been speculating about.

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u/tomas_kimani2 points·3 months ago

discontinuation rate is a result, not a footnote

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