why does nobody talk about SURPASS
Slightly embarrassed to be asking this, but: why does nobody talk about SURPASS. Came off sema and onto tirz with a two-week gap. The first month was flat and I assumed I had made a mistake. Month two it moved. Went 10 to 12.5 on the calendar and had the worst fortnight of the whole run. Dropped back to 10 and…
The distribution matters more than the mean. In the trial population the interquartile spread was wide enough that two honest people can have completely different runs on the same arm.
Sulphur burps for the first eight days after each step, then nothing. Predictable enough that I planned my week around it.
the appetite effect is blunter than sema, in a good way, most weeks
Agreed, and the trial number is a mean of a very wide distribution — the tails are enormous and nobody posts from the middle.
Same experience with the appetite effect being flatter across the week rather than front-loaded.
Appetite effect for me is flat across seven days. On sema it was a wave. Same person, different molecule.
Did you come to this from sema, and if so how long was the gap?
What step are you on and how long have you been there?
What step are you on and how long have you been there?
Not sure about this bit. The GIP arm being real does not tell you that it is what caused your particular week.