[PSA] SURPASS is not what most of this community thinks it is
SURPASS is not what most of this community thinks it is. Two minutes of reading now saves an argument later. Came off sema and onto tirz with a two-week gap. The first month was flat and I assumed I had made a mistake. Month two it moved. Went 10 to 12.5 on the calendar and had the worst fortnight of the whole run.…
It is a dual GIP and GLP-1 receptor agonist, and the GIP arm is the part that has no equivalent in the semaglutide threads. That is why the side-effect profile reads differently rather than just milder.
Does fatigue follow the day after the shot, or is it spread across the week?
[deleted]
dual agonist, so the GIP arm is doing something the sema threads will not tell you about
if 7.5 is working, 10 is not automatically better
switching from sema is not a dose conversion, there is no clean equivalence
Disagree with the conversion table. There is no validated equivalence between the two molecules and posting one as though there is does real damage.
This matches mine. Milder fatigue than I expected, and what there was settled inside a fortnight of each step.
It is a dual GIP and GLP-1 receptor agonist, and the GIP arm is the part that has no equivalent in the semaglutide threads.
Not sure about this bit. The GIP arm being real does not tell you that it is what caused your particular week.