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c/tapering·posted 8 months ago by u/yara_bakken

does discontinuation actually matter or is it forum lore at this point

Results Clean Column ×4 Well Actually ×3

does discontinuation actually matter or is it forum lore at this point. If this has been answered properly somewhere, link me and I will delete.

Why the first fortnight tells you nothing.

With a week-long half-life, exposure declines over several weeks after a final dose rather than ending with it. So the first two weeks after stopping are still a tail of the previous state, and the stability people report in that window is not evidence about the months after it.

The reports here are fairly consistent: appetite noticeably different somewhere in the second month, weight following later, and the trajectory strongly influenced by whether the habits from the losing phase survived. That is not a prediction for anybody in particular, and it is not a schedule — it is the shape of what members describe, which is the most this board can honestly offer.

The habits are what carried it for a while. When they slipped, everything else followed, in that order.

What the evidence says about stopping, written plainly because the framing does real damage.

Withdrawal studies across this class consistently show substantial regain after discontinuation. Appetite typically returns first, well before weight changes. This is a finding about the pharmacology of a chronic condition, in the same way that blood pressure rises again when an antihypertensive is stopped.

People on this board quit in shame over an entirely predictable result, and then avoid coming back because they have interpreted it as a personal failure. It is not. Knowing that in advance is the single most useful thing this board can offer anybody planning to stop.

Please do not ask me what dose you should be on. I genuinely do not know and neither does anyone else here.

8,464 up / 7,507 down53% upvoted40 commentsid if71g817 Nov 2025

40 comments

19 in this archive, depth 4

best — the order this archive was captured in

u/skip_week_scepticMOD115 points·8 months ago

Pointing the clinical part of this at somebody qualified. The experience part can stay here.

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u/ignacio_silva32 points·8 months ago

Stretched from seven days to ten to twelve over four months. Appetite told me where the limit was each time.

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[removed]24 points·8 months ago

[removed by moderator]

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u/dario_vermeulen13 points·8 months ago

interval stretching is the most commonly described approach here

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u/aleksi_lehtinen51 points·8 months ago

With a week-long half-life, exposure declines over several weeks after the last dose rather than stopping with it. The lag is why the first fortnight is uninformative.

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u/cormac_erdogan14 points·8 months ago

Disagree with the framing. Regain is the documented outcome after discontinuation; calling it a personal failure is both wrong and corrosive.

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u/britta_boateng53 points·8 months ago

Has appetite changed yet, independent of the scale?

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u/rekha_teixeira25 points·8 months ago

Same. A quiet fortnight after stopping tells you very little; the interesting part starts later.

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u/zeynep_villalobos11 points·8 months ago

decide what you are watching for before you stop

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u/yara_bakkenOP8 points·8 months ago

Small fix — you have described interval stretching and called it a taper. The exposure profiles differ.

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u/coldchain_karencold chain0 points·8 months ago

decide what you are watching for before you stop

Agreed — and the exposure lag means the first fortnight tells you almost nothing.

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u/rafael_sjoberg32 points·8 months ago

I would not treat appetite returning as a sign of doing it wrong. It is the expected sequence.

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u/andres_restrepo11 points·8 months ago

Careful — interval stretching and dose reduction are different interventions and your post uses them interchangeably.

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u/honest_syringe_202513 points·8 months ago

stretching to ten days then twelve is the pattern people report

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u/fabio_lehtinen25 points·8 months ago

write down where you are before you change anything

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u/neha_mwangi17 points·8 months ago

write down where you are before you change anything

Adding the one process step — write down where you are before you change anything.

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u/ahmed_okafor10 points·8 months ago

Adding the one process step — write down where you are before you change anything.

neha_mwangi is right that regain is a documented outcome rather than a character verdict.

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u/maintenance_mode_maxmaintenance3 points·8 months ago

Push back: that is a taper schedule aimed at another member and this board does not host those.

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About c/tapering

Stopping on purpose: dose reduction versus interval stretching, what the discontinuation arms of STEP 1 and SURMOUNT-4 actually showed about regain, appetite return timelines, and the people who came off, regained, and went back on without treating it as a failure.

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