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c/t2dglp1·posted 7 days ago by u/hamza_weiss

[Results] came off insulin entirely and i still check twice a day

Results

came off insulin entirely and i still check twice a day. Posting the boring middle of the process, because the internet is full of the start and the end and nothing else.

A1c reflects average glycaemia over roughly the preceding three months, weighted towards the most recent weeks. It cannot show variability and it lags any change you make.

On hypoglycaemia, because the risk gets attributed to the wrong thing constantly.

Incretin-based agents stimulate insulin secretion in a glucose-dependent way: the effect scales with glycaemia rather than acting unconditionally. That is why monotherapy risk is low. Where risk rises substantially is in combination with agents that lower glucose independently of the current level.

Which means the question "does this cause hypos" is not answerable without knowing the rest of the regimen — and that the person who can answer it is the one who wrote the regimen. Nothing on this board is a substitute for that conversation, and the good threads here end by saying so.

The order things move in, since nobody explains it and it worries people.

Postprandial excursions generally respond earliest. Variability tends to narrow before the average does, which is visible on a sensor and invisible on a lab result. Fasting glucose is often the laggard, and A1c — being a three-month average — is the last thing to reflect anything.

So a month in which the sensor looks better and the fasting number has not moved is the ordinary sequence, not a contradiction. Knowing that in advance would have saved me a quarter of unnecessary worry, which is why it is worth writing down.

Would rather be corrected in public than confident in private.

0 up / 0 down40% upvoted7 commentsid 1rco2722 Jul 2026

7 comments

7 in this archive, depth 3

best — the order this archive was captured in

u/katrin_girard4 points·6 days ago

Certain conditions affect A1c independently of glycaemia. If a result looks inconsistent with the sensor data, that is a question for whoever manages your care rather than for this board.

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u/hamza_weissOP6 points·6 days ago

time in range is the more informative number and it is newer

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u/fasting_insulin_fMOD3 points·6 days ago

Identifying details redacted from the exported report above.

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u/throwaway_91824 points·6 days ago

postprandial excursions are where most of the improvement shows up first

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u/neha_rahimi5 points·6 days ago

postprandial excursions are where most of the improvement shows up first

Adding the obvious one — bring the export, not the single number, to whoever manages this.

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u/meal_prep_mira1 point·6 days ago

How long between the two A1c measurements?

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u/fasting_insulin_f3 points·6 days ago

hypoglycaemia risk depends far more on what else you take

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About c/t2dglp1

Type 2 diabetes as the original indication: A1c trajectories, CGM traces, hypoglycaemia risk when stacked with sulfonylureas or insulin, metformin combinations, and why the weight-loss conversation sometimes drowns out the glycaemic one.

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