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c/survodutide·submitted 3 months ago by u/cato_girard

[Vendor] BCH vs KP on the same compound, same month — both cleared 98.5%

Paperbranch of 6 comments

Result first, context after: BCH vs KP on the same compound, same month — both cleared 98.5% . Everything below is how it was ordered, stored and sent. Figures up front so nobody has to dig: 98.5%. Read the phase 2 hepatic paper properly and the endpoint definitions were more interesting than the headline response…

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6 comments, started 3 months ago
u/peak_area_peteanalytical11 points·3 months ago

glucagon agonism and energy expenditure is the mechanistic thread

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u/patient_labslip_log7 points·3 months ago

Same. Very thin independent data on this one, which should make everybody here more tentative than they are.

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u/nadia_bakker0 points·3 months ago

glucagon agonism and energy expenditure is the mechanistic thread

Adding the standing caveat — unapproved compound, research material is not for human use.

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u/kaia_cabrera0 points·3 months ago

Adding the standing caveat — unapproved compound, research material is not for human use.

This is the framing the board needs. It is a hepatic programme first.

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u/crosspost_bot_no8 points·3 months ago·edited

That figure is from the obesity programme, and this thread is about the hepatic one.

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u/cold_chromatogram_only5 points·3 months ago

Asked here what the difference was between the imaging and biopsy endpoints and got a genuinely excellent answer.

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Survodutide-specific discussion: glucagon-receptor co-agonism, the hepatic fat and MASH resolution data, and how the side-effect profile compares with GIP-based dual agonism. Small community, high signal.

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