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c/survodutide·submitted 6 months ago by u/fibre_forward

MASH — my 24-week log, condensed into one table

Cautionbranch of 7 comments

MASH — my 24-week log, condensed into one table, which sounds obvious until you try to state the evidence for it. It is a dual agonist at the GLP-1 and glucagon receptors. The glucagon arm is associated with increased energy expenditure and with effects on hepatic fat, which is why the development programme is…

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7 comments, started 5 months ago
u/clara_restrepo62 points·5 months ago

Independent purity results for this compound are very sparse across the whole site, which means any impression about consistency is built on almost nothing.

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u/liver_enzyme_lizMOD34 points·5 months ago

Removed the escalation schedule. Unapproved compound, no protocols for other members, no exceptions.

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u/lyophile_lou50 points·5 months ago

Went slowly because everything published describes a deliberate escalation. That is the extent of what I will say about it.

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u/dario_boateng-35 points·5 months ago

do not import intuitions from the obesity programmes

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u/fibre_forwardOP1 point·5 months ago

What does the tolerability table say at that dose?

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u/patient_labslip_log1 point·5 months ago

Are you reading the publication or a summary?

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u/fibre_forwardOP1 point·5 months ago

How fast was the escalation in that protocol?

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