Ozempic: the version I wish someone had shown me in week 1
Ozempic: the version I wish someone had shown me in week 1. Numbers below. Ask me the boring questions, they are the useful ones. Research-use-only material is not approved for human use, so anything in this thread about how a compounded or research vial "should" behave is a chemistry discussion, not a dosing one. My…
Delayed gastric emptying is most pronounced early and attenuates with continued dosing, which is why the reflux usually fades at a stable dose.
The weekly interval comes out of the half-life — roughly a week — so you are on a smooth curve rather than a series of spikes. That is also why moving your day slightly does very little.
the ladder exists because the gut needs the time, not because the pharmacy likes paperwork
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if 2.4mg is working there is no prize for going up
Delayed gastric emptying is most pronounced early and attenuates with continued dosing, which is why the reflux usually fades at a stable dose.
Right, and the timescale is the bit that keeps getting lost. Judge a step at a month, not at a weekend.
Steady state after a dose change takes four to five half-lives, so the fair judgement point on a new step is about a month, not four days.