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c/semaglutide·posted 10 months ago by u/marta_trevino

tried food noise for 14 weeks. here is what happened.

Question Clean Column ×6 Sourced ×2 Slow Clap ×1

The title is the argument: tried food noise for 14 weeks. here is what happened. Here is the rest of it.

Since the title puts numbers in the shop window: 14 weeks.

First month I lost almost nothing and nearly quit. Month two and three were where it all happened.

The appetite thing was the surprise. I expected to feel full. What I got was simply not thinking about food between meals.

Corrections welcome, especially the pedantic ones. Pedantry is how this board earns its reputation.

3,568 up / 307 down92% upvoted34 commentsid gqt3gn25 Sep 2025

34 comments

30 in this archive, depth 5

best — the order this archive was captured in

u/arne_restrepo664 points·10 months ago

STEP-1 ran 68 weeks and landed just under 15% mean body weight change on 2.4mg. It is an average of a wide distribution, not a target you have missed.

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u/marta_trevinoOP266 points·10 months ago

if 0.5mg is working there is no prize for going up

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u/greta_lokken319 points·10 months ago

Genuine question — is the appetite effect still there, or is it just the scale that has paused?

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u/anya_antonsen208 points·10 months ago

2.4 is a ceiling, not a target

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u/meta_analysis_mo-18 points·10 months ago

nausea made the first fortnight rough at each step up, then flattened out. Predictable enough that I started planning around it.

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u/oskar_kaufmann1 point·10 months ago

the food noise going quiet is the effect people actually describe

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u/freya_baptista1 point·10 months ago·edited

the food noise going quiet is the effect people actually describe

Adding one thing to this: the appetite effect and the scale run on separate clocks, so both halves can be true at once.

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u/marit_coelho1 point·10 months ago

Are you measuring anything other than weight? Waist is usually the one that keeps moving.

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u/slow_logbook_notes1 point·10 months ago

dose day drift of a day either way is fine, the curve barely notices

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u/reflux_report174 points·10 months ago

Dropped my injection day by two days once because of travel. Nothing happened. The panic was worse than the effect.

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u/anya_salgado238 points·10 months ago

Delayed gastric emptying is most pronounced early and attenuates with continued dosing, which is why the nausea usually fades at a stable dose.

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u/vikram_ferreira124 points·10 months ago

Do muscle cramps track the day after the shot, or is it there all week?

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u/ravi_bergstrom103 points·10 months ago

sema is weekly for a reason, the half-life does the smoothing

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u/ahmed_okafor40 points·10 months ago

the first four weeks are a tolerance check, not a weight-loss phase

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u/endpoint_creep11 points·10 months ago

the scale is the least sensitive instrument you own

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u/freya_baptista100 points·10 months ago

Careful. A four-week stall is inside normal variation and treating it as failure is how people escalate for no reason.

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u/archived_thread_a158 points·10 months ago

What I would tell week-one me, in order of how much time it would have saved.

One: the first month is a tolerance check. You are finding out whether you can take this, not how much you will lose. Two: write down the dose, the day and the waist measurement. Three: a stall of under six weeks is weather, not climate. Four: early fullness that arrives the day after the shot and fades by day four is the ordinary pattern and it usually settles at a stable dose.

None of that is advice about what you should do. It is the shape of the thing, which nobody explained to me and which the wiki explains better than I just did.

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u/freya_baptista123 points·10 months ago

Minor fix — the half-life is about a week, not about a day. The rest of your point stands.

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u/ahmed_abubakar97 points·10 months ago

the appetite signal and the scale move on different clocks

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u/vikram_ferreira127 points·10 months ago

Correcting myself from earlier in the thread: I said week 2 and it was week 6. Same shape, wrong number.

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u/vikram_mbeki50 points·10 months ago

the ladder exists because the gut needs the time, not because the pharmacy likes paperwork

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u/arne_amankwah14 points·10 months ago

The weekly interval comes out of the half-life — roughly a week — so you are on a smooth curve rather than a series of spikes. That is also why moving your day slightly does very little.

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u/zofia_lindholm30 points·10 months ago·edited

the ladder exists because the gut needs the time, not because the pharmacy likes paperwork

Right, and the timescale is the bit that keeps getting lost. Judge a step at a month, not at a weekend.

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u/rohan_steiner20 points·10 months ago

Disagree. 2.4 is the top of the label, not the goal, and "everyone ends up there" is just survivorship in the posts you read.

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u/salma_vasquez101 points·10 months ago

Research-use-only material is not approved for human use, so anything in this thread about how a compounded or research vial "should" behave is a chemistry discussion, not a dosing one.

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u/kaplan_meier_kim75 points·10 months ago

On the "everybody ends up at 2.4" claim, which comes up every few weeks.

The escalation schedule in the trials was designed to get people to a fixed study dose. Real use is not a trial. The dose that keeps your appetite quiet with side effects you can live with is the dose, and for a lot of people on this board that has been 0.25mg for a very long time.

The counter-argument, which is fair: some people genuinely do need the top of the range, and staying low out of caution costs them months. That is a conversation with someone who knows your history, not with us.

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u/iman_castellanos108 points·10 months ago

staying at 0.5mg for an extra month is a legitimate plan

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