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Single comment threadYou are looking at one branch of [Meta] the Wegovy rule is doing its job and people should stop complaining — 27 comments in the full submission. View in context.
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c/semaglutide·submitted 1 year ago by u/chidi_demir

[Meta] the Wegovy rule is doing its job and people should stop complaining

Metabranch of 10 comments

Housekeeping: the Wegovy rule is doing its job and people should stop complaining. STEP-1 ran 68 weeks and landed just under 15% mean body weight change on 2.4mg. It is an average of a wide distribution, not a target you have missed. Research-use-only material is not approved for human use, so anything in this thread…

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10 comments, started 1 year ago
u/kenji_demir88 points·1 year ago

Delayed gastric emptying is most pronounced early and attenuates with continued dosing, which is why the reflux usually fades at a stable dose.

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u/anya_salgado37 points·1 year ago

That reads like a titration plan and this board cannot give you one. Somebody who actually knows your history has to.

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u/ffmi_watcher19 points·1 year ago

Minor fix — the half-life is about a week, not about a day. The rest of your point stands.

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u/runa_wikstrom15 points·1 year ago

Cosigning. The appetite change and the scale change ran about three weeks apart for me too.

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u/chidi_demirOP8 points·1 year ago

What dose and how many weeks at it before this started?

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u/test_it_yourselfvetting10 points·1 year ago

the food noise going quiet is the effect people actually describe

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u/chidi_demirOP5 points·1 year ago

Correcting myself from earlier in the thread: I said week 4 and it was week 13. Same shape, wrong number.

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u/elodie_grimaldi2 points·1 year ago

This matches me almost exactly, right down to the muscle cramps showing up on the second day and being gone by the fourth.

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u/stubborn_batchlist_only12 points·1 year ago

Disagree. 2.4 is the top of the label, not the goal, and "everyone ends up there" is just survivorship in the posts you read.

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u/sofia_wikstrom16 points·1 year ago

Kept a log from week one and the single most useful column turned out to be waist, not weight.

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