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c/glp1women·posted 2 months ago by u/bastian_moreau

the fertility thing finally clicked for me and I want to write it down

Results

Posting this as a discussion rather than a claim: the fertility thing finally clicked for me and I want to write it down.

Asked a pharmacist about the absorption question rather than the internet. Ten minutes, clear answer, done.

Fertility changed faster than I expected with the weight loss. Nobody had raised it and I wish somebody had.

The same dose genuinely feels different at different points in the month for me. Took a year to notice and it was in the log the whole time.

Screenshot none of this. Read the whole thread, including the parts where I am told I am wrong.

2,067 up / 2,150 down50% upvoted12 commentsid 13coa65 May 2026

12 comments

12 in this archive, depth 4

best — the order this archive was captured in

u/nils_tulloch14 points·2 months ago

Telogen shedding follows a period of significant weight change rather than a specific compound, and it resolves.

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u/tl_dr_tina11 points·2 months ago

That trial did not enrol the population you are asking about, so it cannot answer this.

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u/hair_shed_hannahMOD15 points·2 months ago

Left up. It is precise about diagnosis versus finding, which makes the answers usable.

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u/mateusz_mensah7 points·2 months ago

Agreed — logging the cycle alongside everything else is what made my own pattern visible. It was invisible before that.

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u/pavel_kravchenko5 points·2 months ago·edited

Has this been raised with whoever prescribes?

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u/tl_dr_tina8 points·2 months ago

Insulin resistance is a common feature in PCOS, which is why the metabolic conversation overlaps so heavily with this board. A diagnosis and a finding are still different things and the distinction matters for what the evidence says.

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[removed]3 points·2 months ago

[removed by moderator]

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u/yusuf_ramos6 points·2 months ago

Hormonal variation across the cycle affects appetite, fluid retention and subjective symptom intensity independently of anything else, which is why an unannotated log can look mysterious.

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u/nayeli_iyer-29 points·2 months ago

Trial populations for the major programmes were not designed around the questions this board asks most often, which is why the evidence base here is genuinely thinner rather than merely harder to find.

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u/neha_rahimi1 point·2 months ago

PCOS is a diagnosis, not a description, and it matters which you mean

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u/gustav_lindholm1 point·2 months ago

Brought the cycle-annotated log to an appointment and it changed the conversation completely.

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About c/glp1women

The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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