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c/coldchain·submitted 2 years ago by u/kian_ekstrom

[Meta] proposal — a flair for cold chain posts

Questionbranch of 10 comments

proposal — a flair for cold chain posts. Short post, long comment section, probably. Asked SSA which lines they hold regionally and got a straight list back. That answered my summer ordering question completely. Split an order across two months deliberately to compare summer and winter transit on the same lane. Four…

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10 comments, started 2 years ago
u/prior_auth_painappeals13 points·2 years ago

Once in solution, the relevant risks are hydrolysis, aggregation and, for some sequences, oxidation. Refrigeration slows all three; freezing a solution introduces a separate risk at the ice interface.

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u/honest_syringe333 points·2 years ago

the excursion that matters is the one after reconstitution

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u/nikhil_asante2 points·2 years ago·edited

the excursion that matters is the one after reconstitution

Agreed, and a logger costs less than the vial you are worrying about.

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u/kian_ekstromOP1 point·2 years ago

Where in the fridge is it sitting now?

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u/iman_castellanos0 points·2 years ago

Same. Door shelf is the worst place in the fridge and it is where everybody puts them.

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u/nightowl_injector1 point·2 years ago·edited

Same.

iman_castellanos is right that the pack failing is not the material failing. Two separate claims.

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u/anya_rautio1 point·2 years ago

the door shelf is the worst place in the fridge

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u/cesar_teixeira11 points·2 years ago

lyophilised powder is far more forgiving than the panic threads suggest

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u/reship_roulette3 points·2 years ago

a summer lane and a winter lane are different lanes

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u/kian_ekstromOP4 points·2 years ago

Which lane, and had it been quoted at that transit time?

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About c/coldchain

Temperature and stability in the real world: what an excursion actually costs you, why lyophilised powder is far more forgiving than reconstituted solution, how to read a logger CSV, and how to photograph a failed shipment so the conversation with the vendor is short.

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