[Meta] proposal — a flair for rodent data posts
Putting this to the board: proposal — a flair for rodent data posts. The evidence base, described honestly, which almost no summary of it does. The published literature is overwhelmingly preclinical and largely in rodent models. The individual papers are generally more modest in their claims than the summaries that…
Research-use-only material is not approved for human use. In this board that is not a formality — it is the reason the clinical evidence base is as thin as it is.
no clinical trial has established what these threads assert
Agreed. Identity is the question here. A short peptide can be synthesised by almost anyone and the sequence is what you are actually buying.
Agreed.
Adding the standing caveat — research material is not approved for human use, wherever you are.
most of the claims here trace to the same handful of rodent papers
Short peptides in solution are subject to hydrolysis and, depending on sequence, oxidation. Storage state and time in solution are practical variables that this board almost never discusses.
Right, and regulatory status has genuinely moved in several jurisdictions. Answers from three years ago may be wrong now.
Kept a reconstituted vial too long out of curiosity and learned something about solution stability I would rather have read.