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c/bloodwork·posted 2 years ago by u/copay_card_cc

[PSA] ALT is not what most of this community thinks it is

Question Receipts ×3 Cold Box ×1 Slow Clap ×2

ALT is not what most of this community thinks it is. That is the post. The justification is underneath.

Time of day, fasting state, hydration and recent exercise all move common markers. Standardising the draw conditions is free and it removes most of the apparent variability.

ApoB counts atherogenic particles rather than the cholesterol they carry, which is why it can diverge from LDL-C and why it is the addition most worth making.

Reference intervals are typically the central 95% of a reference population. By construction one person in twenty falls outside one on any given test without anything being wrong.

Ask me anything specific. Anything general I will probably get wrong.

3,082 up / 328 down90% upvoted16 commentsid 11lgas11 Jul 2024

16 comments

2 in this archive, depth 1

best — the order this archive was captured in

u/gentle_correctionMOD435 points·2 years ago

Identifying header cropped from the report above. Post the values, not the name and reference number.

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u/sanne_novak303 points·2 years ago

Different laboratories use different assay platforms with different calibration. Comparing across labs adds a systematic offset that is invisible on the report.

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About c/bloodwork

What to measure before you start, what to re-measure, and how to interpret movement without panicking. ApoB over LDL-C, HOMA-IR as a crude free tool, ALT and the fatty-liver story, eGFR noise during rapid loss, and the deficiencies that a 1,100-calorie appetite will hand you.

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