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c/bloodwork·submitted 2 years ago by u/milos_trevino

reading eGFR threads from 2024 and half of it aged badly

Baselinebranch of 7 comments

reading eGFR threads from 2024 and half of it aged badly. I have gone back and forth on this for months. Different laboratories use different assay platforms with different calibration. Comparing across labs adds a systematic offset that is invisible on the report. Reference intervals are typically the central 95% of…

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7 comments, started 2 years ago
u/micro_bump_mick189 points·2 years ago

Nobody here can interpret your panel and this comment is not doing so. What a board can usefully do is help you ask better questions of somebody who can.

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u/ismael_eriksen101 points·2 years ago

Time of day, fasting state, hydration and recent exercise all move common markers. Standardising the draw conditions is free and it removes most of the apparent variability.

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u/skip_week_sceptic62 points·1 year ago

Agreed. The trend is the signal. A single value is a snapshot of one morning.

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u/milos_trevinoOP0 points·1 year ago

Did anything else change in that window — training, intake, hydration?

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u/milos_trevinoOP1 point·1 year ago

Small fix — a reference interval is not a treatment target, and the post above uses them interchangeably.

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[removed]1 point·1 year ago

[removed by moderator]

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u/amara_dziedzic38 points·1 year ago

Agreed.

Agreed — and standardising the draw conditions is the cheapest improvement available.

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