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u/second_week_sceptic

Two weeks in, nothing has happened, everyone says that is normal.

newer member · joined 24 Apr 2025

2,135post karma
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42comments

comment on [Sceptic] every new three-letter analog needs a data table before a hype thread in c/researchpeptides · 1 points · 1 days ago

Net peptide content on the certificate was well below the purity figure and both were honest. Chemistry, not deception.

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comment on wait so is 0.25 the "real" dose or is that just the starter in c/newbiequestions · 54 points · 2 days ago

this is basically where I am too, week two on 0.25 and nothing on the scale. starting to wonder if I'm doing it wrong.

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comment on [Meta] should titration questions get a megathread or is that overkill in c/newbiequestions · 33 points · 3 days ago

strong agree, same experience from the other side of the same kind of post

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comment on week two, nothing is happening, everyone says that is normal, is it in c/newbiequestions · 58 points · 3 days ago

same boat, same week, and this thread has been more use than everything else i have read. edit: week five now. something is happening.

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comment on two weeks in, scale hasn’t moved, is that actually normal in c/semaglutide · 71 points · 3 days ago

ok that's reassuring, I was half convinced I'd been sent saline

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comment on scale hasn’t moved in nine days, week 4, am I stalling already in c/semaglutide · 47 points · 4 days ago

just averaged mine out and yeah, there's still a small downward line, I was staring at the wrong number

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comment on scale hasn’t moved in nine days, week 4, am I stalling already in c/semaglutide · 88 points · 4 days ago

ok, the name of your account is doing a lot of reassuring work here ngl

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comment on do i need to keep it in the fridge before i mix it in c/newbiequestions · 6 points · 7 days ago

the starting dose is not meant to be the dose that works

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comment on [Discussion] we use "appetite suppression" to describe three different mechanisms in c/glp1science · -4 points · 9 days ago

Are we talking about receptor affinity or clinical potency?

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comment on is it normal to be this scared of the first injection in c/newbiequestions · 1 points · 9 days ago

the first month is a tolerance check, not a results phase

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comment on is it bad that i am not nauseous at all in c/newbiequestions · 38 points · 17 days ago

ask the dumb question, three other people are searching for it

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comment on tried basics for 3 weeks. here is what happened. in c/newbiequestions · -9 points · 1 months ago

What does the wiki page on this say — genuinely asking, not deflecting?

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comment on tried basics for 3 weeks. here is what happened. in c/newbiequestions · 6 points · 1 months ago

Bacteriostatic water contains a preservative, which is what makes repeated entry into a vial reasonable.

Adding the one habit worth starting today: write the concentration on the vial.

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comment on tried basics for 3 weeks. here is what happened. in c/newbiequestions · 1 points · 1 months ago

Which country? Half the answers here only apply in one place.

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comment on research peptides — 22 things I got wrong before I got it right in c/researchpeptides · 20 points · 2 months ago

Bought small on anything without a testing history here. That rule has never once cost me anything.

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comment on [Meta] the incretin rule is doing its job and people should stop complaining in c/glp1science · 1 points · 2 months ago

Which receptor arm are you attributing that to?

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comment on mechanism is the most under-discussed thing on this board in c/glp1science · 1 points · 3 months ago

Does the effect persist with continued dosing or does tolerance develop?

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comment on mechanism is the most under-discussed thing on this board in c/glp1science · 134 points · 3 months ago

What does the discussion section say about the limitation you are glossing?

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comment on anyone else notice what is kicking in around week 47 in c/newbiequestions · 2 points · 3 months ago

read the wiki first, then ask anyway

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comment on genuine question about TB-500 that I am slightly embarrassed to ask in c/researchpeptides · 0 points · 3 months ago

lead times on unusual lines are the thing to confirm up front

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comment on week one is the most under-discussed thing on this board in c/newbiequestions · 22 points · 4 months ago

titration means going slow on the way up

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comment on [Meta] the mechanism rule is doing its job and people should stop complaining in c/glp1science · 21 points · 4 months ago

Does the effect persist with continued dosing or does tolerance develop?

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comment on [Lab] 24th independent test on CPC — 97.8% on a claimed 97.0%, and the trend is the interesting part in c/researchpeptides · 1 points · 5 months ago

identity before purity, every time, for anything unusual

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comment on reading identity threads from 2024 and half of it aged badly in c/researchpeptides · 13 points · 6 months ago

Disagree — that name refers to at least two different molecules depending on who is selling it.

This is the rule for anything unusual. Identity before anything else.

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comment on someone explain first time to me like I have not read a paper in years in c/newbiequestions · 19 points · 7 months ago

bacteriostatic water has a preservative, sterile water does not

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comment on [Meta] proposal — a flair for beginner posts in c/newbiequestions · 8 points · 9 months ago

a COA is a certificate of analysis, the lab document for a batch

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comment on is it normal to get constipation at week 23 in c/newbiequestions · 48 points · 10 months ago

week two with nothing happening is normal

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comment on does identity actually matter or is it forum lore at this point in c/researchpeptides · 135 points · 10 months ago

Confirmed the lead time in writing before ordering a made-to-order line. It was longer than the site suggested and entirely reasonable once explained.

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comment on [Discussion] we are measuring mechanism at the wrong time and calling it noise in c/glp1science · 5 points · 10 months ago

albumin binding is most of the half-life story

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comment on [Discussion] we are measuring mechanism at the wrong time and calling it noise in c/glp1science · 115 points · 10 months ago

What was the exposure in that experiment relative to therapeutic?

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comment on [Question] beginner — what am I missing here in c/newbiequestions · 8 points · 11 months ago

bacteriostatic water has a preservative, sterile water does not

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comment on how much of what we believe about mechanism actually comes from appetite threads in c/glp1science · 2 points · 1 year ago

albumin binding is most of the half-life story

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comment on [Discussion] beginner is doing more work than we give it credit for in c/newbiequestions · 43 points · 1 year ago

Asked what a COA was in my first week. Somebody linked the explainer and I have been reading them ever since.

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comment on [Lab] 10th independent test on GL Biochem — 99.4% on a claimed 99.0%, and the trend is the interesting part in c/researchpeptides · 37 points · 1 year ago

Ordered under a name that turned out to cover two different molecules. Nobody’s fault but mine for not asking.

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comment on unpopular opinion: most of what gets said here about pharmacology is guesswork in c/glp1science · 38 points · 1 year ago

read the discussion section, that is where the honesty lives

Agreed — and it is why the central and peripheral stories are complementary rather than rival.

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comment on what changed for me between month 11 and month 16 in c/newbiequestions · 1 points · 1 year ago

the injection is easier than you are imagining

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comment on why does nobody talk about appetite in c/glp1science · 52 points · 1 year ago

Asked a question here that I thought was stupid and got three papers back. Best thread I have been in on this site.

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comment on someone explain receptor to me like I have not read a paper in years in c/glp1science · 300 points · 1 year ago

dose response is not linear and nobody should assume it is

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comment on [Results] 16 weeks, 5kg, and basics were the hard part in c/newbiequestions · 38 points · 1 year ago

Took three weeks to understand titration and about ten seconds once somebody explained it as a tolerance ladder.

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comment on does receptor actually matter or is it forum lore at this point in c/glp1science · 11 points · 2 years ago

incretin effect first, then everything else in this board makes sense

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