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u/cesar_ivaturi

Contributes reviews on supplier material. Based in Osijek.

member · joined 14 May 2025

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Overview — page 2 of 3

comment on [Meta] the import rule is doing its job and people should stop complaining in c/customs · 6 points · 6 months ago

What documentation accompanied the shipment?

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comment on [Meta] proposal — a flair for mg/mL posts in c/reconstitution · 63 points · 7 months ago

the number you write down is the number you will trust at 6am

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comment on the dead space thing finally clicked for me and I want to write it down in c/reconstitution · 66 points · 7 months ago

Bacteriostatic water contains benzyl alcohol as a preservative, which is what makes repeated entry into the same vial reasonable. Plain sterile water has no preservative.

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comment on SURPASS — 12 things I got wrong before I got it right in c/trialwatch · 126 points · 7 months ago

Careful with that mean. The distribution around it was wide enough that it describes very few individual participants.

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comment on [Question] dead space — what am I missing here in c/reconstitution · 23 points · 7 months ago

Did the maths give you a whole number of units, or a fraction?

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comment on genuine question about COA that I am slightly embarrassed to ask in c/coa · 59 points · 8 months ago

Small fix — 214nm, not 280nm.

Adding the bit that always gets missed: the lot on the vial has to match the lot on the page, or none of this applies to your material.

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comment on [Vendor] GL Biochem order #4 — Germany, 12 days, no drama, receipts inside in c/customs · 1 points · 8 months ago

Not convinced. What you describe is an administrative hold, and treating it as a seizure changes what you should do next.

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comment on [Lab] 12th independent test on QST — 98.6% on a claimed 98.5%, and the trend is the interesting part in c/coa · 88 points · 8 months ago

Area percent or net peptide content? They answer different questions.

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comment on reading bacteriostatic water threads from 2024 and half of it aged badly in c/reconstitution · 1 points · 9 months ago

The arithmetic in full: concentration is mass over volume, so 20mg into 3mL gives 6.67mg/mL. A U-100 syringe is graduated at 100 units per millilitre, so 1mg is 1 divided by 6.67 millilitres, which is 15 units.

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comment on [Meta] the FLOW rule is doing its job and people should stop complaining in c/trialwatch · 1 points · 9 months ago

Relative risk reduction without the baseline rate is uninterpretable.

Adding the check nobody runs — the registered protocol is public and takes two minutes to compare.

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comment on [Meta] the FLOW rule is doing its job and people should stop complaining in c/trialwatch · 2 points · 9 months ago

FLOW was kidney outcomes and it is the one nobody quotes

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comment on [Meta] proposal — a flair for related substances posts in c/coa · 4 points · 9 months ago

Agreed — the itemised related substances table is the difference between a document and a receipt.

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comment on unpopular opinion: most of what gets said here about mg/mL is guesswork in c/reconstitution · 1 points · 9 months ago

the number you write down is the number you will trust at 6am

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comment on [Question] how do you actually verify crypto in c/cryptopay · 102 points · 9 months ago

screenshot the transaction hash, not the wallet balance

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comment on [Vendor] TFC order #8 — Denmark, 12 days, no drama, receipts inside in c/cryptopay · 2 points · 10 months ago

This. A test transaction on a large order costs a fraction of the fee and removes the whole class of risk.

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comment on [Discussion] MASH is doing more work than we give it credit for in c/survodutide · 0 points · 11 months ago

Cosigning on the glucagon arm. It is the mechanistic thread that connects the hepatic and the metabolic effects.

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comment on three years of seizure threads, summarised so you do not have to read them in c/customs · 138 points · 11 months ago

A hold, a request for information and a seizure are distinct administrative events. Each has its own process and deadlines, and the notice itself states which one you have.

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comment on the STEP thing finally clicked for me and I want to write it down in c/trialwatch · 10 points · 11 months ago

a press release is not a publication

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comment on [Vendor] SWB order #6 — Ireland, 13 days, no drama, receipts inside in c/cryptopay · 1 points · 11 months ago

escrow arrangements are rare and worth asking about

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comment on [Discussion] the endpoint advice in here is 3 years out of date in c/trialwatch · 48 points · 12 months ago

That is a relative risk reduction. Quoting it without the absolute numbers overstates the case considerably.

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comment on genuine question about MASH that I am slightly embarrassed to ask in c/survodutide · 1 points · 1 year ago

I would not read across from the obesity programmes. Different population, different endpoint, different question.

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comment on [Question] how do you actually verify biopsy in c/survodutide · 22 points · 1 year ago

Sent a vial to PeptideMeter because there was nothing on file. 97.4% against a claimed 97.0%. First entry for this compound in my own log.

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comment on [Question] how do you actually verify jurisdiction in c/customs · 28 points · 1 year ago

How long has it been sitting, and at which stage?

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comment on [Question] how do you actually verify jurisdiction in c/customs · 54 points · 1 year ago

ask the supplier what documentation accompanies the shipment

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comment on [Question] how do you actually verify jurisdiction in c/customs · 41 points · 1 year ago

Is there a deadline on the notice?

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comment on SURPASS — 11 things I got wrong before I got it right in c/trialwatch · 205 points · 1 year ago

intention to treat versus completers changes the number substantially

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comment on small win: MASH stopped being a problem at week 43 in c/survodutide · 50 points · 1 year ago

Agreed that the endpoint definitions matter enormously and almost nobody reads them before quoting a response rate.

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comment on units — 21 things I got wrong before I got it right in c/reconstitution · 80 points · 1 year ago

units are a volume on a U-100 syringe, not a dose

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comment on reading declared value threads from 2024 and half of it aged badly in c/customs · 161 points · 1 year ago

Correction: that is a request for information, not a seizure notice. Different document, different process, different deadline.

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comment on genuine question about dual agonist that I am slightly embarrassed to ask in c/survodutide · 4 points · 1 year ago

MASH endpoints are histological, which is a much harder bar

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comment on related substances — 9 things I got wrong before I got it right in c/coa · 27 points · 1 year ago

Correction: that is net peptide content, not purity.

amira_dumitru has the distinction right — one is a fraction of the detector signal, the other is a fraction of the mass.

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comment on jurisdiction — 14 things I got wrong before I got it right in c/customs · 1 points · 1 year ago

I would not read a single clearance experience as a rule. Sample size one, and customs is not deterministic.

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comment on unpopular opinion: most of what gets said here about confirmations are guesswork in c/cryptopay · 10 points · 1 year ago

Escrow is not standard in this space. Wanting it is reasonable; expecting it as default is not.

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comment on someone explain mg/mL to me like I have not read a paper in years in c/reconstitution · 156 points · 1 year ago

reconstituting at a round concentration makes every later dose easy

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comment on unpopular opinion: most of what gets said here about area percent is guesswork in c/coa · 15 points · 1 year ago

Pushing back a little: a missing field is usually presentation, not concealment.

Agreed, and the practical version is: ask for the itemised table. If it exists, you get it.

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comment on [Lab] Homopeptide survo — Medutest came back 98.4% against a claimed 98.0% in c/survodutide · 31 points · 1 year ago

read the histology endpoint definitions before quoting a response rate

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comment on three years of COA threads, summarised so you do not have to read them in c/coa · 7 points · 1 year ago

Small fix — 214nm, not 280nm. It matters here because the impurity you are asking about barely absorbs at the longer wavelength.

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comment on does SELECT actually matter or is it forum lore at this point in c/trialwatch · 70 points · 1 year ago

open-label extensions are not the same evidence as the randomised phase

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comment on help me understand dead space, I have read the wiki twice in c/reconstitution · 129 points · 1 year ago

Asked WWB what volume they reconstitute to for their own stability testing and they answered in one line. Useful thing to know.

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