131
why does nobody talk about CagriSema
why does nobody talk about CagriSema. I am not trying to be the "source?" guy. I would just like a source. Why this compound is not simply another agonist, which is how…
satiety
Every GLP Research Hub submission tagged to satiety, ranked by score. Discussed in 1 community.
Communities covering this
120
[Lab] first independent cagrilintide purity number i have seen
Right: first independent cagrilintide purity number i have seen. I paid for this one myself, nobody sent me anything, and the receipts are in the comments. The…
103
[Discussion] cagri is the most underrated molecule in this space
Thinking out loud about this: cagri is the most underrated molecule in this space. Nothing containing this compound is approved as a standalone product, and…
92
[Lab] SGN cagri — VendorInvestigate came back 97.4% against a claimed 97.0%
SGN cagri — VendorInvestigate came back 97.4% against a claimed 97.0%, and before anyone asks: same batch throughout, single submission, no cherry-picking between…
Sigma-Aldrich — certified reference materials
Reference standards, analytical reagents and system-suitability material. If you are running your own method, start with a known.
Reference standards68
amylin is not a GLP-1 and the co-agonism story is more interesting than the weight number
The hill I will die on. Cagrilintide is a long-acting amylin analog and people keep filing it mentally as "more GLP-1". Amylin signalling and GLP-1 signalling converge…
56
what would you tell week-1 you about cagrilintide
what would you tell week-1 you about cagrilintide, and I want the answer with the reasoning attached rather than just the conclusion. Why this compound is not simply…
0
[Question] why does the satiety feel qualitatively different
Trying to get a straight answer on this: why does the satiety feel qualitatively different. Reading the trial literature on this without misleading yourself. Separate…
0
what changed for me between month 9 and month 14
The title is the whole question — what changed for me between month 9 and month 14 — but here is why I am asking. Dosing intuitions from the GLP-1 boards do not…
0
three years of CagriSema threads, summarised so you do not have to read them
three years of CagriSema threads, summarised so you do not have to read them. I have gone back and forth on this for months. Combination and monotherapy arms must be…
0
someone explain satiety to me like I have not read a paper in years
Question in the title, detail here: someone explain satiety to me like I have not read a paper in years. Amylin is co-secreted with insulin and acts on satiety and…
0
23 months in and satiety is still the thing I get wrong
Here it is: 23 months in and satiety is still the thing I get wrong. One person, one log, no control group, so read it accordingly. The numbers the title promised,…
-72
[Question] how do you actually verify satiety
Genuine question, and the title is the question: how do you actually verify satiety. Bought small deliberately because the evidence base is thin. That felt like the…