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c/trialwatch·submitted 1 months ago by u/milan_villalobos

[Question] how do you actually verify SURPASS

Statsbranch of 6 comments

Slightly embarrassed to be asking this, but: how do you actually verify SURPASS. Argued for a week about a result and then read the limitations section, which conceded most of my opponent’s point. On means, which this board treats as targets and which are nothing of the sort. A reported mean body weight change is the…

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6 comments, started 1 months ago
u/customs_seizure_sid46 points·1 months ago

A confidence interval is the range of effects compatible with the data. Two trials with overlapping intervals have not disagreed, whatever their point estimates look like next to each other.

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u/line_demir34 points·1 months ago

Quoted a figure here confidently, got asked whether it was ITT, went and checked, and it was not. Learned something.

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u/injection_site_iris30 points·1 months ago·edited

Do you have the publication or the press release?

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u/milan_villalobosOP19 points·1 months ago

SURPASS is the diabetes programme and reports glycaemic endpoints

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[removed]33 points·1 months ago

[removed by moderator]

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u/receipts_or_nothingvetting12 points·1 months ago

Right — trial participants get structured support. Comparing yourself to a trial mean is comparing across two different interventions.

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