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c/tirzepatide·submitted 1 year ago by u/customs_seizure_sid

what changed for me between month 6 and month 14

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what changed for me between month 6 and month 14. Searched first, found three threads that contradict each other, hence the post. Appetite effect for me is flat across seven days. On sema it was a wave. Same person, different molecule. 24kg over 93 weeks, never went past 10mg, and fatigue stayed mild the whole way.…

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6 comments, started 1 year ago

u/titration_marshalMOD505 points·1 year ago

Trial identifiers corrected in the title. SURMOUNT and SURPASS are different programmes.

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u/customs_seizure_sidOP397 points·1 year ago

SURMOUNT-1 landed around 21% at 72 weeks on the top arm

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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