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c/tirzepatide·submitted 10 months ago by u/ewan_marchand

[Results] 74 weeks, 23kg, and GIP was the hard part

Resultsbranch of 8 comments

Here it is: 74 weeks, 23kg, and GIP was the hard part. One person, one log, no control group, so read it accordingly. 74 weeks and 23kg. Those are measured, not estimated, and not rounded up in my favour. 8kg over 21 weeks, never went past 10mg, and muscle cramps stayed mild the whole way. Posting because the loud…

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8 comments, started 10 months ago
u/emil_barros773 points·10 months ago·edited

Vials and pens carry the same molecule; what differs is fill volume, device tolerance and whether you are doing your own arithmetic. Neither is inherently more accurate.

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u/ewan_marchandOP438 points·10 months ago

Appetite effect for me is flat across seven days. On sema it was a wave. Same person, different molecule.

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u/signe_villalobos415 points·10 months ago

Are you comparing yourself with the trial mean or with the people who post the most?

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[removed]152 points·10 months ago

[removed by moderator]

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u/customs_seizure_sid335 points·10 months ago

What is the waist doing? That is usually the number still moving during a scale stall.

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u/ignacio_vanhecke95 points·10 months ago

The four-week interval in the label is a minimum. Nothing about the pharmacology requires you to step on schedule, and the trials stepped on a calendar because trials have to.

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Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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