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c/tirzepatide·submitted 1 year ago by u/zeynep_zielinski

[Results] 63 weeks on 5mg, full numbers, ask me anything boring

Resultsbranch of 6 comments

Reporting in. 63 weeks on 5mg, full numbers, ask me anything boring. 63 weeks and 5mg — those are the numbers, and they are the ones I am willing to defend. Came off sema and onto tirz with a two-week gap. The first month was flat and I assumed I had made a mistake. Month two it moved. Sulphur burps for the first…

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6 comments, started 1 year ago
u/quiet_moderatorMOD182 points·1 year ago

This is the fifth "should I go up" post today and they are all welcome — but no member here can answer it for you.

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[deleted]119 points·1 year ago

[deleted]

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u/georgi_chowdhury38 points·1 year ago

The 21% figure is a 72-week mean on the highest arm. Quoting it as what someone should expect by week 43 is not a fair reading.

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u/tarek_kirchner87 points·1 year ago

pens and vials are the same molecule, the price is the difference

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u/ewan_marchand30 points·1 year ago

pens and vials are the same molecule, the price is the difference

Not sure about this bit. The GIP arm being real does not tell you that it is what caused your particular week.

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u/gustav_vermeulen28 points·1 year ago

I would separate the two claims. That the GIP arm exists is uncontroversial; that it explains your sulphur burps pattern is a guess.

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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