how much of what we believe about Mounjaro actually comes from Zepbound threads
Asking properly rather than in a comment on somebody else’s thread: how much of what we believe about Mounjaro actually comes from Zepbound threads. On comparing yourself with the trial number. SURMOUNT-1 reported roughly 21% mean body weight change at 72 weeks on the highest arm. Three things get dropped every time…
Weekly dosing again, half-life in the same neighbourhood as sema, so a step change takes about a month to reach steady state. Judging a new step at day five is judging noise.
Removed the conversion table. There is no published equivalence between the two molecules and posting one as fact is exactly the kind of thing that gets copied for years.
2.5mg is a four-week starting dose, not a maintenance dose. Worth being precise since people search these threads.
SURMOUNT-1 ran 72 weeks with the top arm around 21% mean body weight change. SURPASS is the diabetes programme and reports glycaemic endpoints, so quoting the two interchangeably is a category error.
Sulphur burps for the first eight days after each step, then nothing. Predictable enough that I planned my week around it.
That percentage is body weight change, not body fat. Different measurement, and the distinction gets lost every time.
Agreed, and the trial number is a mean of a very wide distribution — the tails are enormous and nobody posts from the middle.