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c/tirzepatide·submitted 5 days ago by u/customs_seizure_sid

is the tirz appetite thing actually different or am i imagining it

Titrationbranch of 7 comments

is the tirz appetite thing actually different or am i imagining it. If this has been answered properly somewhere, link me and I will delete. Switching from semaglutide, since three people asked in this thread alone. There is no published dose equivalence between the two. The conversion tables that circulate are…

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7 comments, started 4 days ago
u/hub_opssite staff19 points·4 days ago

switching from sema is not a dose conversion, there is no clean equivalence

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u/zaid_balogun6 points·3 days ago

2.5 is the starter dose and it is not meant to be the dose that works

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u/elin_varga5 points·3 days ago

2.5 is the starter dose and it is not meant to be the dose that works

Not sure about this bit. The GIP arm being real does not tell you that it is what caused your particular week.

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u/vito_chowdhury1 point·3 days ago

Push back: "gentler than sema" is a population statement. Plenty of people on this board have the opposite experience and they are not doing it wrong.

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[deleted]1 point·3 days ago

[deleted]

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u/swirl_dont_shakereconstitution1 point·2 days ago

Which week did the appetite change actually land for you?

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u/customs_seizure_sidOP-1 point·4 days ago·edited

switching from sema is not a dose conversion, there is no clean equivalence

Saving this one. It is the clearest statement of the stall problem I have read here.

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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