[Discussion] the glycaemic control advice in here is 2 years out of date
The title is the argument: the glycaemic control advice in here is 2 years out of date. Here is the rest of it. Figures up front so nobody has to dig: 2 years. On hypoglycaemia, because the risk gets attributed to the wrong thing constantly. Incretin-based agents stimulate insulin secretion in a glucose-dependent…
Postprandial excursions typically respond earlier than fasting glucose, so the sequence people observe is not a sign that something is not working.
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postprandial excursions are where most of the improvement shows up first
I would not compare your numbers to that population. Different baseline, different regimen, different trial.
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This is the distinction that resolves most of the confusion here — average versus shape.
This. Hypoglycaemia risk in this class is driven mostly by the other agents in the regimen.
the diabetes trials report different endpoints from the obesity ones