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c/t2dglp1·posted 2 months ago by u/teodor_duarte

someone explain glycaemic control to me like I have not read a paper in years

Question Receipts ×2

Slightly embarrassed to be asking this, but: someone explain glycaemic control to me like I have not read a paper in years.

Time in range told me far more than the average did. Two quarters with the same A1c looked completely different on the sensor.

Assumed the weight endpoints from the obesity trials applied to my situation. They are different programmes.

Brought the whole CGM export to my appointment rather than one number. Entirely different conversation.

Corrections welcome, especially the pedantic ones. Pedantry is how this board earns its reputation.

2,727 up / 2,020 down57% upvoted42 commentsid 1t4st119 May 2026

42 comments

4 in this archive, depth 3

best — the order this archive was captured in

u/fasting_insulin_f91 points·2 months ago

The order things move in, since nobody explains it and it worries people.

Postprandial excursions generally respond earliest. Variability tends to narrow before the average does, which is visible on a sensor and invisible on a lab result. Fasting glucose is often the laggard, and A1c — being a three-month average — is the last thing to reflect anything.

So a month in which the sensor looks better and the fasting number has not moved is the ordinary sequence, not a contradiction. Knowing that in advance would have saved me a quarter of unnecessary worry, which is why it is worth writing down.

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u/teodor_duarteOP61 points·2 months ago

Postprandial excursions flattened out first and the fasting number took months to follow. Nobody had told me to expect that order.

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u/marta_weiss48 points·2 months ago

hypoglycaemia risk depends far more on what else you take

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u/hamza_weiss0 points·2 months ago

Push back: one sensor reading is not a data point worth acting on, especially in the first day of wear.

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About c/t2dglp1

Type 2 diabetes as the original indication: A1c trajectories, CGM traces, hypoglycaemia risk when stacked with sulfonylureas or insulin, metformin combinations, and why the weight-loss conversation sometimes drowns out the glycaemic one.

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