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c/semaglutide·submitted 9 months ago by u/dead_space_doug

titration: what the trials say vs what this community says

Titrationbranch of 7 comments

Posting this as a discussion rather than a claim: titration: what the trials say vs what this community says. Weight change and appetite change are different endpoints on different timescales. Conflating them is where most of the confusion on this board starts. Delayed gastric emptying is most pronounced early and…

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7 comments, started 9 months ago
u/careful_gradient_again281 points·9 months ago

Sat at 1.7mg for four months because it was doing the job. Everyone told me to go up. The one time I did, the only thing that changed was the injection-site soreness.

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u/rina_bergstrom64 points·9 months ago

Sat at 1.7mg for four months because it was doing the job.

Disagree with this specific line. A pause at 0.25mg is not evidence that 0.25mg has stopped working.

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u/careful_gradient_again53 points·9 months ago

Did protein intake change in the same window?

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[removed]207 points·9 months ago

[removed by moderator]

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u/dead_space_dougOP160 points·9 months ago

stalling at 2.4mg is information, not a verdict

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u/dead_space_doug149 points·9 months ago

The appetite thing was the surprise. I expected to feel full. What I got was simply not thinking about food between meals.

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u/tomas_kimani190 points·9 months ago

How long was the stall before you decided it was a stall?

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