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Single comment threadYou are looking at one branch of genuine question about Wegovy that I am slightly embarrassed to ask — 55 comments in the full submission. View in context.
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c/semaglutide·submitted 2 years ago by u/ravi_sandvik

genuine question about Wegovy that I am slightly embarrassed to ask

PSAbranch of 12 comments

genuine question about Wegovy that I am slightly embarrassed to ask. I would rather ask a basic question now than get this wrong quietly for two months. Steady state after a dose change takes four to five half-lives, so the fair judgement point on a new step is about a month, not four days. The escalation schedule in…

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12 comments, started 2 years ago
u/units_not_mgMOD449 points·2 years ago

Removed the dose recommendation. You can describe what you did; you cannot tell somebody else what to take.

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u/hassan_castellanos213 points·2 years ago

Removed the dose recommendation.

This is the part I would underline for anyone skimming. Everything else in the thread is downstream of it.

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u/units_not_mgsyringe math129 points·2 years ago

What dose and how many weeks at it before this started?

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u/bilal_osei231 points·2 years ago·edited

Did protein intake change in the same window?

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u/customs_seizure_sid126 points·2 years ago

Agreed, and the bit people skip is that the ladder is a tolerance ladder. It is not a potency ranking.

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u/camila_sandvik68 points·2 years ago·edited

That figure is the 68-week trial mean, not a weekly rate. Dividing it by the weeks gives you a number that does not mean anything.

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u/rafael_ostergaard52 points·2 years ago

I would push back gently. Going up because the scale paused is the single most common mistake described on this board.

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u/iman_castellanos126 points·2 years ago

Strongly agree on protein. It did more for my muscle cramps than any of the things I bought to fix my muscle cramps.

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u/micro_bump_mick179 points·2 years ago

The weekly interval comes out of the half-life — roughly a week — so you are on a smooth curve rather than a series of spikes. That is also why moving your day slightly does very little.

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u/ahmed_abubakar55 points·2 years ago

week 17 plateau is the most predictable thing in this entire board

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