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c/semaglutide·submitted 12 days ago by u/camila_mensa

why does everyone say week 4 is the wall

Discussionbranch of 7 comments

Here it is: why does everyone say week 4 is the wall. One person, one log, no control group, so read it accordingly. The mental model that finally made this click for me: there are two curves, and people watch the wrong one. The first is exposure, which is set by the dose and smoothed by a week-long half-life. It…

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7 comments, started 12 days ago
u/iman_falk24 points·12 days ago

Week 38: 13kg down, muscle cramps basically gone since about week 2, and the honest headline is that nothing dramatic happened. It was boring and it worked.

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[deleted]18 points·12 days ago

[deleted]

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u/vikram_mbeki7 points·12 days ago

Kept a log from week one and the single most useful column turned out to be waist, not weight.

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u/careful_gradient_again19 points·11 days ago

the first four weeks are a tolerance check, not a weight-loss phase

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u/ines_castellanos13 points·11 days ago

STEP-1 averaged just under 15% at 68 weeks, so a 10% year is not a failure

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u/dose_creep_dan13 points·11 days ago

the first four weeks are a tolerance check, not a weight-loss phase

This is the part I would underline for anyone skimming. Everything else in the thread is downstream of it.

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u/niels_lindqvist8 points·11 days ago

This is the part I would underline for anyone skimming.

Disagree with this specific line. A pause at 0.25mg is not evidence that 0.25mg has stopped working.

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