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c/semaglutide·posted 1 months ago by u/zeynep_weiss

appetite came back at week 30 and i panicked for no reason

Results Cold Box ×4 Slow Clap ×2 Long Haul ×3

Reporting in. appetite came back at week 30 and i panicked for no reason.

STEP-1 ran 68 weeks and landed just under 15% mean body weight change on 2.4mg. It is an average of a wide distribution, not a target you have missed.

The escalation schedule in the trials existed to keep people on the drug. It is a tolerability ramp, and it is why the label reads the way it does.

Corrections welcome, especially the pedantic ones. Pedantry is how this board earns its reputation.

3,435 up / 210 down94% upvoted31 commentsid 1cnw0816 Jun 2026

31 comments

6 in this archive, depth 3

best — the order this archive was captured in

u/test_it_yourselfvetting438 points·1 months ago

Weight change and appetite change are different endpoints on different timescales. Conflating them is where most of the confusion on this board starts.

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u/osman_ferrari512 points·1 months ago

Delayed gastric emptying is most pronounced early and attenuates with continued dosing, which is why the reflux usually fades at a stable dose.

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[deleted]220 points·1 months ago

[deleted]

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u/units_not_mgsyringe math295 points·1 months ago·edited

I would push back gently. Going up because the scale paused is the single most common mistake described on this board.

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u/hassan_castellanos75 points·1 months ago

My stall was eleven weeks. Eleven. Then it moved again without me changing anything at all.

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