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Single comment threadYou are looking at one branch of [Lab] split one vial across VendorInvestigate and PeptideMeter — 94.2% and 97.9% — 38 comments in the full submission. View in context.
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c/semaglutide·submitted 2 years ago by u/greta_lokken

[Lab] split one vial across VendorInvestigate and PeptideMeter — 94.2% and 97.9%

Side Effectsbranch of 13 comments

Result first, context after: split one vial across VendorInvestigate and PeptideMeter — 94.2% and 97.9% . Everything below is how it was ordered, stored and sent. Numbers, in the order they matter: 94.2% and 97.9%. Kept a log from week one and the single most useful column turned out to be waist, not weight. Dropped…

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13 comments, started 2 years ago
u/lane_map_larrylogistics40 points·2 years ago

The weekly interval comes out of the half-life — roughly a week — so you are on a smooth curve rather than a series of spikes. That is also why moving your day slightly does very little.

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u/plain_titration9 points·2 years ago

the appetite signal and the scale move on different clocks

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u/yara_boateng3 points·2 years ago

dose day drift of a day either way is fine, the curve barely notices

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u/aleksi_grimaldi11 points·2 years ago

do not chase somebody else’s titration schedule, they are not you

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u/micro_bump_mick7 points·2 years ago

Disagree. 2.4 is the top of the label, not the goal, and "everyone ends up there" is just survivorship in the posts you read.

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u/b12_baseline14 points·2 years ago

Not convinced. You changed the dose and the week at the same time, so you cannot attribute the change to either.

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u/gustav_solberg3 points·2 years ago

My stall was eleven weeks. Eleven. Then it moved again without me changing anything at all.

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u/arne_amankwah9 points·2 years ago

Steady state after a dose change takes four to five half-lives, so the fair judgement point on a new step is about a month, not four days.

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u/elodie_grimaldi4 points·2 years ago

protein first, then everything else gets easier

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u/niels_lindqvist2 points·2 years ago

Correct, and worth adding: the trial average is an average. Half the people in it did worse than 15% and were still on the drug.

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u/careful_gradient_again3 points·2 years ago

protein first, then everything else gets easier

Adding one thing to this: the appetite effect and the scale run on separate clocks, so both halves can be true at once.

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u/hugo_bergstrom4 points·2 years ago

the scale is the least sensitive instrument you own

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u/zofia_lindholm14 points·2 years ago

the ladder exists because the gut needs the time, not because the pharmacy likes paperwork

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