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c/reconstitution·submitted 1 year ago by u/ledger_mod

[Discussion] the insulin syringe advice in here is 2 years out of date

Discussionbranch of 7 comments

the insulin syringe advice in here is 2 years out of date, and I am aware this is a minority view on this board. The numbers the title promised, since a headline without them is worthless: 2 years. Everything below is context for those. Shook the first vial because nobody told me not to. It was fine, but I have…

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7 comments, started 1 year ago
u/quarter_dose_queenlow and slow37 points·1 year ago

The arithmetic in full: concentration is mass over volume, so 20mg into 2mL gives 10mg/mL. A U-100 syringe is graduated at 100 units per millilitre, so 5mg is 5 divided by 10 millilitres, which is 50 units.

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u/ledger_modOPmod · vetting22 points·1 year ago·edited

Spent 18 weeks confused about this until somebody drew the table for me. 20mg, 3mL, 6.67mg/mL, 2mg is 30 units. That is the whole thing.

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u/julia_erdogan11 points·1 year ago

if the maths gives you a fraction of a unit, change the concentration

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u/ledger_modOPmod · vetting8 points·1 year ago

Small fix — a U-100 syringe is 100 units per mL. If yours is marked differently it is not U-100 and the whole calculation changes.

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u/declared_value_dv5 points·1 year ago

twice as much water halves the concentration and doubles the units for the same dose

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u/ledger_modOPmod · vetting-13 points·1 year ago

The arithmetic in full: concentration is mass over volume, so 20mg into 2mL gives 10mg/mL.

Disagreeing with this line only: adding more water is not a safety margin, it is a different divisor.

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u/escrow_evangelist1 point·1 year ago·edited

Yes. Writing 30mg/mL on the vial takes four seconds and removes the entire class of error this board exists to fix.

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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