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c/reconstitution·posted 2 years ago by u/ledger_mod

[Discussion] the units advice in here is 2 years out of date

Discussion Receipts ×9

the units advice in here is 2 years out of date, and I am aware this is a minority view on this board.

Hard numbers: 2 years. Anything softer than that is flagged as an impression.

Aim the stream down the wall of the vial rather than into the cake. Reconstitution is a solubility problem, not a mixing problem, and mechanical shear does nothing helpful.

If your calculation produces a fraction of a unit, the concentration is wrong for your dose. Change the water volume until the numbers land on whole units.

Research-use-only material is not approved for human use and nothing here should be read as a recommendation to use it.

0 up / 0 down50% upvoted4 commentsid fbktye19 Apr 2024

4 comments

4 in this archive, depth 4

best — the order this archive was captured in

u/priya_weiss6 points·2 years ago

Bacteriostatic water contains benzyl alcohol as a preservative, which is what makes repeated entry into the same vial reasonable. Plain sterile water has no preservative.

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u/hub_opssite staff2 points·2 years ago

write the concentration on the vial in marker, that is the whole post

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u/cesar_ivaturi2 points·2 years ago

Small fix — a U-100 syringe is 100 units per mL. If yours is marked differently it is not U-100 and the whole calculation changes.

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u/arto_falk2 points·2 years ago

do the arithmetic before you reconstitute, not while holding a syringe

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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