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c/reconstitution·submitted 2 months ago by u/adaeze_cabrera

[Meta] the units rule is doing its job and people should stop complaining

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the units rule is doing its job and people should stop complaining. Short post, long comment section, probably. Research-use-only material is not approved for human use, so treat everything in this thread as arithmetic about solutions rather than instructions for a person. I keep a laminated card in the drawer with…

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6 comments, started 2 months ago
u/ledger_modmod · vetting6 points·2 months ago

Not quite. Bacteriostatic and sterile water are not interchangeable for a multi-draw vial, and the difference is the preservative.

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u/reflux_report2 points·2 months ago

Agreed on the swirl. There is no reason to shake it and a good reason not to.

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u/sigrid_kaufmann1 point·2 months ago·edited

Agreed on the swirl.

Right, and the arithmetic behind it: 15mg in 3mL is 5mg/mL, so 0.5mg is 10 units.

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u/adaeze_cabreraOP1 point·2 months ago

Wrote the date on the vial as well as the concentration after losing track of which one was opened first.

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u/elin_ferrari1 point·2 months ago

the powder cake sits at the bottom, the volume you add is the volume that counts

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u/RetaAndRegret21 point·2 months ago

the powder cake sits at the bottom, the volume you add is the volume that counts

Disagreeing with this line only: adding more water is not a safety margin, it is a different divisor.

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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