[Question] small molecule — what am I missing here
small molecule — what am I missing here. Searched first, found three threads that contradict each other, hence the post. Compared milligram figures across two completely different molecule classes in a comment. Deserved the correction. Went looking for independent testing on this and found essentially nothing, which…
That is a phase 2 result being quoted as though the programme had reported.
That is a phase 2 result being quoted as though the programme had reported.
Adding the standing caveat — unapproved, and research material is not for human use.
oral and non-peptide is the whole engineering story
the tolerability profile reads broadly similar to the class
the tolerability profile reads broadly similar to the class
chidi_yilmaz is right that milligram comparisons across classes tell you nothing.
The no-timing-restriction thing is the part I would care about most in practice, and it barely gets mentioned here.
Cosigning on daily dosing. It changes the exposure profile and it changes adherence, in both directions.
ATTAIN and ACHIEVE are the programmes to keep straight