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c/orforglipron·submitted 1 year ago by u/marit_coelho

[Lab] QYB orfo — Medutest came back 99.2% against a claimed 99.0%

Trial Databranch of 9 comments

QYB orfo — Medutest came back 99.2% against a claimed 99.0%. One vial, one service, one member paying, which is the only kind of result this board should treat as evidence. 99.2% and 99.0% — those are the numbers, and they are the ones I am willing to defend. Oral semaglutide is a peptide co-formulated with an…

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9 comments, started 1 year ago
u/phase_two_peteMOD290 points·1 year ago

Left up. It is careful about what is peptide and what is not, which is more than most threads here manage.

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u/neha_mwangi91 points·1 year ago

oral semaglutide is a peptide with an absorption enhancer, this is not that

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u/marit_sandvik72 points·1 year ago

Push back: daily dosing is not automatically better adherence. It is a different failure mode, not a solved problem.

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u/emeka_delgado50 points·1 year ago

Milligram-for-milligram comparison with an injectable peptide is not meaningful and I should not have made it.

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u/bastian_ekstrom15 points·1 year ago

daily dosing changes adherence in both directions

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u/neha_krastev82 points·1 year ago

Disagree. You are comparing doses across a small molecule and a peptide, which is not a comparison of anything.

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[deleted]199 points·1 year ago

[deleted]

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u/flair_enthusiast290 points·1 year ago

Is that from the publication or the press release?

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u/hazard_ratio_halstats90 points·1 year ago

Agreed — non-peptide is the fact that everything else follows from, including the manufacturing and the analytics.

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