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c/glp1women·submitted 1 year ago by u/ewan_tulloch

[Discussion] we are measuring contraception at the wrong time and calling it noise

Discussionbranch of 7 comments

we are measuring contraception at the wrong time and calling it noise. Not a hot take, just something I have not seen said plainly here. Went looking for trial data on the specific question asked here and found the population had not been enrolled. Asked a pharmacist about the absorption question rather than the…

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7 comments, started 1 year ago
u/kaia_fonseca94 points·1 year ago

cycle timing changes how the same week feels

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u/ines_boateng23 points·1 year ago

Hormonal variation across the cycle affects appetite, fluid retention and subjective symptom intensity independently of anything else, which is why an unannotated log can look mysterious.

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u/lukas_vermeulen16 points·1 year ago

That is a general statement about gastric emptying, and the question was about a specific product.

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u/neha_falk14 points·1 year ago

Hormonal variation across the cycle affects appetite, fluid retention and subjective symptom intensity independently of anything else, which is why an

This is the practical fix for half the confusing weeks on this board — annotate the cycle.

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u/nils_tulloch7 points·1 year ago

This is the practical fix for half the confusing weeks on this board — annotate the cycle.

Disagreeing with this line: the absorption question has a product-specific answer and a pharmacist has it.

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u/rasmus_petrescu4 points·1 year ago

Disagreeing with this line: the absorption question has a product-specific answer and a pharmacist has it.

nils_tulloch is right that a diagnosis and a finding are different things here.

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u/ines_boateng9 points·1 year ago

Same. Perimenopause overlapping with all of this is the least documented area on the whole site.

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The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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